Product image of Olfen Gel (Diclofenac Sodium) supplied by GNH India

Olfen Gel

Active Ingredient:
Diclofenac Sodium
Origin:
EU

Olfen Gel (Diclofenac Sodium)

Diclofenac sodium, the active ingredient in Olfen Gel, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a topical gel for cutaneous use. It reduces inflammation and alleviates pain associated with musculoskeletal conditions, sports injuries, sprains, strains and arthritis in adults.

GNH India supplies Olfen Gel as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies, and clinics worldwide for professional use. The company adheres to stringent quality assurance protocols and ensures regulatory compliance across EU and other markets.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Diclofenac sodium gel is a topical NSAID that acts on inflammatory pathways to relieve pain and swelling.
  • Musculoskeletal pain: provides localized pain relief at the application site.
  • Sports injuries: reduces inflammation and supports faster recovery.
  • Sprains and strains: alleviates swelling and discomfort.
  • Arthritis: diminishes joint pain and stiffness.

How It Works

  • Diclofenac sodium inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes in peripheral tissues, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis limits inflammation, pain signaling, and edema at the site of application.

Side Effects

Topical application of diclofenac sodium may cause local and systemic adverse reactions.

Common Side Effects

  • Skin irritation at the site of application.
  • Redness or erythema.
  • Burning or stinging sensation.
  • Pruritus (itching).
  • Dryness of the skin.
  • Localized itching.

Serious or Rare Side Effects

  • Allergic contact dermatitis.
  • Systemic NSAID effects such as gastrointestinal ulceration.
  • Elevated liver enzymes indicating hepatic involvement.
  • Severe skin reactions, including Stevens‑Johnson syndrome.

Precautions & Warnings

  • When using Olfen Gel, consider the following precautions.
  • Apply to intact skin: avoid broken or infected areas.
  • Limit area of application: do not exceed 10% of body surface at one time.
  • Avoid concurrent systemic NSAIDs: increased risk of systemic toxicity.
  • Use with caution in patients with cardiovascular disease: monitor for edema.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Olfen Gel may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Concurrent oral NSAIDs: heightened risk of systemic toxicity.
  • Anticoagulants (e.g., warfarin, DOACs): increased bleeding tendency.
  • Systemic corticosteroids: additive risk of gastrointestinal ulceration.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: possible impact on renal function.
  • Lithium: potential rise in serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Olfen Gel contains diclofenac sodium and is indicated for the topical relief of pain and inflammation associated with musculoskeletal conditions, sports‑related injuries, sprains, strains, and osteoarthritis. It is applied directly to the affected skin area to target local symptoms.

Diclofenac sodium works by reversibly inhibiting cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins—key mediators of inflammation, pain, and swelling. Lower prostaglandin levels diminish the inflammatory response at the site where the gel is applied.

The specific amount and frequency of Olfen Gel application are determined by the prescribing healthcare professional based on the severity of symptoms and the size of the treatment area. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of topical diclofenac during pregnancy or lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks with their healthcare provider before using Olfen Gel.

To order Olfen Gel, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Olfen Gel delivers diclofenac locally, which can reduce systemic exposure compared with oral formulations. This topical route often results in fewer gastrointestinal side effects while still providing effective pain relief for localized conditions. Compared with other NSAID gels, its efficacy and safety profile are similar, but individual response may vary.

Olfen Gel should be stored at room temperature, preferably below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight, and extreme temperatures to maintain product stability.

Apply a thin layer of Olfen Gel to clean, dry skin over the affected area, gently massaging it in until absorbed. The prescriber may advise applying the gel 2–4 times daily, but patients should follow the specific instructions given by their healthcare professional.

Serious risks include severe allergic reactions such as contact dermatitis, systemic NSAID‑related effects like gastrointestinal ulceration or bleeding, and rare but life‑threatening skin conditions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice widespread rash, blistering, or signs of systemic toxicity.

Olfen Gel should be avoided in individuals with known hypersensitivity to diclofenac or other NSAIDs, in patients with active skin infections or open wounds at the intended application site, and in those with a history of severe cardiovascular, renal, or hepatic disease unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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