Product image of Olfen Retard (Diclofenac Sodium) supplied by GNH India

Olfen Retard

Active Ingredient:
Diclofenac Sodium
Origin:
EU

Olfen Retard (Diclofenac Sodium)

Diclofenac sodium, the active ingredient in Olfen Retard, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral administration. It is classified as an analgesic, anti‑inflammatory and antirheumatic agent and is used to relieve pain and reduce inflammation in adult patients with musculoskeletal disorders such as osteoarthritis and rheumatoid arthritis.

GNH India supplies Olfen Retard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other healthcare facilities worldwide.

Manufacturer / TM Owner

Teva Pharma – Produtos Farmacêuticos Lda

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Olfen Retard (diclofenac sodium) is indicated for conditions involving pain and inflammation within the musculoskeletal system.

  • Osteoarthritis: reduces joint pain and improves mobility.
  • Rheumatoid arthritis: decreases inflammation and joint swelling.
  • Acute pain: provides relief from moderate to severe pain such as postoperative or injury‑related pain.

How It Works

  • Diclofenac sodium inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin synthesis, it diminishes inflammation, pain signaling, and fever responses in affected tissues, producing its analgesic and anti‑inflammatory effects.

Side Effects

Like other NSAIDs, diclofenac sodium may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia.
  • Nausea or vomiting.
  • Headache.
  • Dizziness.
  • Mild skin rash.
  • Elevated blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Significant liver enzyme elevation or hepatitis.
  • Renal impairment or failure.
  • Severe hypersensitivity reactions (e.g., Stevens‑Johnson syndrome).
  • Cardiovascular events such as myocardial infarction or stroke.
  • Blood dyscrasias including agranulocytosis.

Precautions & Warnings

Before initiating therapy, clinicians should evaluate individual risk factors and monitor patients regularly.

  • Gastrointestinal risk: assess history of ulcers or bleeding before use.
  • Cardiovascular caution: avoid in patients with established heart disease or high thrombotic risk.
  • Renal function: monitor kidney function, especially in dehydrated or elderly patients.
  • Hepatic monitoring: check liver enzymes periodically during prolonged therapy.
  • Pregnancy and lactation: contraindicated in late pregnancy; use only if benefits outweigh risks.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Avoid Interactions

Diclofenac sodium can interact with several drug classes, requiring careful assessment.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • SSRIs or SNRIs: heightened risk of bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may enhance renal adverse effects.
  • Methotrexate: potential for increased toxicity.

Frequently Asked Questions

Olfen Retard contains diclofenac sodium, an NSAID that is used to relieve pain and reduce inflammation associated with musculoskeletal conditions such as osteoarthritis, rheumatoid arthritis, and acute moderate‑to‑severe pain following surgery or injury.

Diclofenac sodium blocks the cyclooxygenase (COX‑1 and COX‑2) enzymes, preventing the formation of prostaglandins that mediate inflammation, pain, and fever. This inhibition reduces the inflammatory response and alleviates pain at the site of injury or disease.

The appropriate dose of Olfen Retard is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, and overall health status. Patients should follow the specific dosing instructions provided by their healthcare professional.

Diclofenac sodium is generally avoided in the third trimester of pregnancy because of potential fetal cardiovascular effects. Use during pregnancy or lactation should only occur when the prescriber judges that the benefit outweighs the risk, and it is typically not recommended without specialist advice.

To place an order, submit an enquiry on the Olfen Retard product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Both diclofenac (Olfen Retard) and ibuprofen belong to the NSAID class and share similar mechanisms of COX inhibition. Diclofenac is often considered more potent on a milligram‑per‑milligram basis, but it may carry a higher risk of cardiovascular and gastrointestinal adverse events compared with ibuprofen, requiring individualized risk assessment.

Olfen Retard should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

Olfen Retard is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can help reduce gastrointestinal discomfort. Patients should swallow the tablet whole and not split, crush, or chew it unless directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe liver injury, renal failure, cardiovascular events such as heart attack or stroke, and rare but life‑threatening hypersensitivity reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs such as black stools, persistent abdominal pain, jaundice, sudden swelling, or rash.

Olfen Retard should be avoided in individuals with known hypersensitivity to diclofenac or other NSAIDs, active gastrointestinal ulceration or bleeding, severe heart failure, uncontrolled hypertension, and in the third trimester of pregnancy. Caution is also advised for patients with impaired liver or kidney function, and it should be used only under medical supervision in these groups.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.