Oliclinomel N4-550e (Glycine, Olive Oil, Refined, Soya-Bean Oil Refined, Magnesium Chloride Hexahydrate, Potassium Chlori)

Oliclinomel N4-550e is used in clinical nutrition to provide essential nutrients for patients who cannot receive enteral feeding.

• Post‑operative patients: helps maintain caloric and protein needs during recovery.
• Critical‑care patients: supplies necessary amino acids and electrolytes when oral intake is not possible.
• Long‑term parenteral nutrition: sustains nutritional status for patients with chronic gastrointestinal failure.

• Oliclinomel N4-550e delivers a balanced mixture of amino acids, electrolytes and lipid emulsions directly into the bloodstream, bypassing the gastrointestinal tract. The formulation provides glycine and other amino acids for protein synthesis, magnesium and potassium for electrolyte balance, and refined olive and soybean oils as a source of essential fatty acids, supporting cellular metabolism and energy production.

Adverse reactions may occur with any intravenous nutrition product and should be monitored during therapy.

Common Side Effects

• Phlebitis at the infusion site: inflammation of the vein.
• Mild hypertriglyceridemia: slight increase in blood triglyceride levels.
• Transient electrolyte imbalance: temporary changes in potassium or magnesium levels.
• Fever or chills: mild temperature elevation during infusion.
• Nausea: occasional feeling of queasiness.

Serious or Rare Side Effects

• Severe allergic reaction (anaphylaxis): rapid onset of hives, airway swelling, or hypotension.
• Acute liver dysfunction: marked elevation of liver enzymes.
• Hyperosmolar hyperglycaemic state: high blood glucose in susceptible patients.
• Pulmonary embolism: rare clot formation linked to lipid emulsions.
• Sepsis seeding: infection risk from contaminated infusion sets.

When using Oliclinomel N4-550e, clinicians should assess patient suitability and monitor therapy closely.

• Assess renal function: adjust electrolyte content if renal impairment is present.
• Monitor electrolytes: regular checks of potassium and magnesium levels are recommended.
• Observe infusion site: watch for signs of phlebitis or infiltration.
• Evaluate liver function: periodic liver enzyme testing may be needed.
• Review lipid tolerance: consider triglyceride levels in patients with hyperlipidaemia.
• Store at 2-8°C: keep refrigerated, protect from light ; avoid freezing and shake before use.

Oliclinomel N4-550e may interact with other intravenous therapies and medications that affect electrolyte balance.

Major Interactions (Avoid)

• Concurrent high‑dose potassium chloride: risk of hyper‑kalemia.
• Magnesium‑containing infusions or supplements : increased risk of hyper‑magnesium.
• Lipid‑based parenteral nutrients : potential overload of caloric intake.\nModerate Interaction M ":[

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