Product image of Olimel E (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Olimel E

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Olimel E (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

A mixture of essential and non‑essential amino acids, the active ingredient in Olimel E, is an amino acid solution presented as a solution for injection for intravenous use. It provides nutrition for patients who cannot receive enteral feeding, such as postoperative, trauma, or critically ill patients.

GNH India supplies Olimel E as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Baxter Deutschland Gmbh

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Indications & Clinical Uses

Olimel E is used in parenteral nutrition to meet protein and nitrogen requirements in patients unable to tolerate enteral feeding.

  • Postoperative patients: supports protein synthesis and nitrogen balance during recovery.
  • Trauma patients: provides essential amino acids for tissue repair and metabolic needs.
  • Critically ill patients: maintains nitrogen balance when oral/enteral intake is insufficient.
  • Severely malnourished patients: supplies amino acids to prevent catabolism.
  • Major surgery patients: aids postoperative healing and immune function.

How It Works

  • Olimel E delivers a balanced mixture of essential and non‑essential amino acids directly into the bloodstream. The amino acids are taken up by cellular transporters and incorporated into proteins, supporting protein synthesis, nitrogen balance, and various metabolic pathways essential for tissue repair and immune function in patients receiving parenteral nutrition.

Side Effects

Adverse reactions may occur with intravenous amino acid solutions.

Common Side Effects

  • Hyperglycemia: elevated blood glucose levels.
  • Electrolyte disturbances: changes in potassium, sodium, or calcium.
  • Infusion site reactions: redness, pain, or swelling.
  • Nausea or vomiting.
  • Headache.
  • Fever.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction.
  • Metabolic acidosis: abnormal blood pH.
  • Hepatic dysfunction: liver enzyme elevations.
  • Hyperammonemia: elevated ammonia levels.
  • Renal impairment: decreased kidney function.
  • Thrombophlebitis: vein inflammation with clot formation.

Precautions & Warnings

When using Olimel E, clinicians should consider several safety measures.

  • Renal function assessment: evaluate kidney status before initiation.
  • Hepatic function monitoring: check liver enzymes regularly.
  • Electrolyte and glucose monitoring: adjust infusion as needed.
  • Dose adjustment in liver or kidney disease: tailor therapy to organ function.
  • Hypersensitivity screening: avoid in patients with known amino acid allergies.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Olimel E may interact with other medications or solutions.

Major Interactions (Avoid)

  • Concurrent high‑dose potassium supplements: risk of hyperkalemia.
  • Co‑administration with other parenteral nutrition solutions: risk of nutrient overload.
  • Use with nephrotoxic drugs: increased renal stress.
  • Combination with insulin therapy: potential hypoglycemia.
  • Simultaneous diuretic therapy: electrolyte imbalance.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may alter protein catabolism.
  • Beta‑agonists: can affect serum potassium levels.
  • Anticoagulants: possible impact on clotting parameters.
  • Additional amino acid products: monitor cumulative amino acid load.

Frequently Asked Questions

Olimel E is an intravenous amino acid solution used as part of parenteral nutrition. It supplies essential and non‑essential amino acids to patients who cannot receive enteral feeding, helping to meet protein and nitrogen needs in postoperative, trauma, and critically ill individuals.

The mixture provides a balanced profile of amino acids that are rapidly absorbed into the bloodstream. Cells take up these amino acids via specific transporters and incorporate them into proteins, supporting tissue repair, immune function, and overall nitrogen balance during intravenous nutrition therapy.

The dose of Olimel E is individualized and set by the prescribing clinician based on the patient’s weight, metabolic status, and nutritional requirements. No fixed regimen is provided; dosing is calculated to achieve the desired protein and nitrogen targets.

Safety data for Olimel E in pregnancy and lactation are limited. The decision to use it in pregnant or nursing patients should be made by the treating physician after weighing potential benefits against any possible risks to the mother and child.

To order Olimel E, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Olimel E offers a comprehensive blend of essential and non‑essential amino acids in a single formulation, which can simplify compounding compared with multi‑component kits. Its EU‑origin manufacturing ensures compliance with European quality standards, making it comparable to other high‑quality parenteral amino acid products.

Olimel E must be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before administration, inspect for particulate matter or discoloration and use aseptic technique throughout preparation and infusion.

Olimel E is administered intravenously, typically as a continuous infusion or intermittent infusion according to the clinician’s prescription. The solution is added to a compatible infusion set, and infusion rates are adjusted to meet the patient’s calculated protein and nitrogen requirements.

Serious risks include anaphylactic reactions, metabolic acidosis, hepatic dysfunction, hyperammonemia, renal impairment, and thrombophlebitis. Patients should be closely monitored for signs of these events, and therapy should be discontinued immediately if severe adverse reactions occur.

Olimel E should be avoided in patients with known hypersensitivity to any of its amino acid components. Caution is also advised for individuals with severe hepatic or renal failure, uncontrolled metabolic disorders, or those receiving incompatible intravenous medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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