Olimel N12 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Olimel N12 provides amino acids that act within the protein‑building pathway and is used in clinical nutrition contexts.

• Metabolic disorders: Helps maintain nitrogen balance in patients with catabolic states.
• Post‑surgical recovery: Supports tissue repair and wound healing.
• Malnutrition: Contributes to improved nutritional status in undernourished individuals.
• Critical illness: Assists in preserving lean body mass during intensive care.
• Chronic kidney disease: Provides a controlled source of amino acids with limited nitrogen load.

• The amino‑acid blend supplies the body with substrates required for protein synthesis, stimulates the mTOR signaling pathway and provides nitrogen for the formation of new muscle and tissue proteins. By delivering essential and conditionally essential amino acids, it helps restore nitrogen balance and supports cellular metabolism in catabolic or nutritionally compromised states.

Amino‑acid supplementation is generally well tolerated, but adverse reactions can occur.

Common Side Effects

• Nausea: mild gastrointestinal upset.
• Abdominal discomfort: bloating or mild cramps.
• Diarrhoea: loose stools, usually transient.
• Headache: mild, self‑limiting.
• Metallic taste: temporary alteration of taste perception.

Serious or Rare Side Effects

• Allergic reaction: rash, itching, or swelling.
• Hyperammonemia: elevated blood ammonia in susceptible individuals.
• Metabolic acidosis: rare disturbance of acid‑base balance.
• Severe gastrointestinal intolerance: persistent vomiting or diarrhoea.
• Anaphylaxis: life‑threatening hypersensitivity requiring emergency care.

When using Olimel N12, consider the following safety measures:

• Renal impairment: dose adjustment may be needed.
• Hepatic dysfunction: monitor liver function tests.
• Pregnancy: limited evidence; use only if clearly needed.
• Pediatric use: safety data are limited; prescribe only by specialist consultation.
• Concomitant nutrition therapy: assess total protein intake to avoid excess.
• Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Amino‑acid mixtures may interact with certain medicines and nutrients.

Major Interactions (Avoid)

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