Product image of Olimel N12 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Olimel N12

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Olimel N12 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N12, is a parenteral nutrition supplement presented as a nutritional formulation for intravenous use. It provides essential amino acids for patients requiring nutritional support, particularly in critical care and postoperative settings.

GNH India supplies Olimel N12 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.

Manufacturer / TM Owner

Baxter Medical Ab

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Indications & Clinical Uses

Olimel N12 is used as a component of parenteral nutrition regimens to support patients with complex metabolic needs.

  • Critical illness: helps maintain nitrogen balance and supports protein synthesis.
  • Post‑operative recovery: provides essential amino acids to aid wound healing.
  • Severe malnutrition: supplies necessary building blocks when oral intake is insufficient.
  • Long‑term home parenteral nutrition: sustains nutritional status for patients unable to eat orally.

How It Works

  • Olimel N12 supplies a balanced mixture of essential and non‑essential amino acids that are directly absorbed into the bloodstream during intravenous infusion. The amino acids serve as substrates for protein synthesis, support gluconeogenesis, and contribute to nitrogen balance, thereby helping to meet the metabolic demands of critically ill or nutritionally compromised patients.

Side Effects

Adverse reactions to Olimel N12 are generally related to its intravenous administration and amino‑acid composition.

Common Side Effects

  • Mild fever or chills during infusion.
  • Transient increase in blood urea nitrogen.
  • Local irritation at the infusion site.
  • Mild electrolyte disturbances (e.g., potassium shifts).
  • Headache.
  • Nausea.

Serious or Rare Side Effects

  • Anaphylactic or severe hypersensitivity reaction.
  • Metabolic acidosis.
  • Hyperammonemia.
  • Severe electrolyte imbalance (e.g., hyperkalemia, hypocalcemia).
  • Thrombophlebitis at the catheter site.
  • Renal dysfunction exacerbation.

Precautions & Warnings

When prescribing Olimel N12, clinicians should consider patient‑specific factors and monitor relevant parameters.

  • Renal impairment: adjust infusion rate and monitor nitrogen waste.
  • Hepatic dysfunction: watch for signs of hyperammonemia.
  • Electrolyte disorders: check serum electrolytes before and during therapy.
  • Fluid overload risk: assess volume status, especially in cardiac patients.
  • Allergic history: verify no known hypersensitivity to amino‑acid solutions.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Olimel N12 may interact with other intravenous solutions or medications that affect nitrogen balance and electrolyte status.

Major Interactions (Avoid)

  • High‑dose potassium chloride admixtures: risk of hyperkalemia.
  • Acidic drug solutions (e.g., certain antibiotics): may precipitate amino acids.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: can exacerbate electrolyte shifts.
  • Corticosteroids: may increase protein catabolism, altering amino‑acid requirements.
  • Other parenteral nutrition components: ensure compatible mixing ratios.
  • Anticoagulants: monitor clotting parameters if central line is used.

Frequently Asked Questions

Olimel N12 is an intravenous amino‑acid formulation used as part of parenteral nutrition to provide essential building blocks for protein synthesis in patients who cannot meet their nutritional needs orally, such as those in critical care, after surgery, or with severe malnutrition.

The blend delivers a balanced profile of essential and non‑essential amino acids directly into the bloodstream, supporting protein synthesis, nitrogen balance, and metabolic processes like gluconeogenesis, which are vital for recovery and maintenance of lean body mass in nutritionally compromised patients.

The prescribed dose of Olimel N12 is individualized by the treating clinician based on the patient’s weight, metabolic needs, and clinical condition. Healthcare professionals calculate the appropriate infusion rate and total daily amount according to established parenteral nutrition guidelines.

Safety data for Olimel N12 in pregnancy and lactation are limited. It should only be used when clearly needed and when the potential benefits outweigh any possible risks, under the supervision of a qualified healthcare provider.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.

Olimel N12 offers a comprehensive mix of ten essential amino acids, providing a balanced profile that matches many standard amino‑acid formulations. Compared with products that contain additional non‑essential amino acids or specialized ratios, Olimel N12 is suited for general nutritional support where a broad amino‑acid spectrum is required.

Store Olimel N12 at ambient temperature, preferably below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and extreme temperature fluctuations. Do not freeze; inspect the solution for particulate matter before use.

Olimel N12 is administered intravenously, typically diluted in a compatible carrier fluid and infused over a prescribed period using an infusion pump. Administration must follow aseptic technique and be performed by trained healthcare personnel.

Serious risks include severe hypersensitivity reactions such as anaphylaxis, metabolic acidosis, hyperammonemia, and significant electrolyte disturbances. Monitoring of vital signs, laboratory parameters and infusion site is essential to detect and manage these events promptly.

Patients with known hypersensitivity to any component of the amino‑acid solution, those with uncontrolled severe electrolyte imbalances, or individuals in whom rapid fluid overload would be hazardous should avoid Olimel N12 unless a risk‑benefit assessment justifies its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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