Product image of Olimel N7e (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Olimel N7e

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Olimel N7e (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredients in Olimel N7e, are essential amino acids presented as a powder for oral use. They are employed to support protein synthesis and nutritional rehabilitation in patients requiring amino acid supplementation.

GNH India supplies Olimel N7e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Baxter A/S

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Indications & Clinical Uses

Olimel N7e provides essential amino acids that support metabolic pathways involved in protein synthesis and nutritional recovery.

  • Protein‑energy malnutrition: helps restore nitrogen balance and promote lean body mass gain.
  • Post‑operative recovery: supplies substrates for tissue repair and wound healing.
  • Chronic kidney disease (stable): assists in maintaining essential amino acid levels while limiting excess nitrogen load.
  • Severe burns or trauma: provides rapid amino acid replenishment to support catabolic stress response.

How It Works

  • The essential amino acids in Olimel N7e act as substrates for ribosomal protein synthesis, activating the mTOR signaling pathway and enhancing muscle protein accretion. By supplying the building blocks for peptide bonds, the formulation helps restore nitrogen balance, supports tissue repair, and mitigates catabolism in states of increased metabolic demand.

Side Effects

Amino acid supplementation may be associated with a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Diarrhea: loose stools in some individuals.
  • Abdominal discomfort: cramping or bloating.
  • Headache: transient mild headache.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Metabolic acidosis: rare disturbance of acid‑base balance in susceptible patients.
  • Hyperuricemia: elevated uric acid levels in predisposed individuals.
  • Hyperammonemia: increased ammonia concentrations, particularly in severe renal impairment.

Precautions & Warnings

When considering Olimel N7e, several precautionary measures should be observed to ensure safe use.

  • Assess renal function: avoid or adjust use in severe renal impairment.
  • Monitor hepatic status: contraindicated in severe liver disease due to altered amino acid metabolism.
  • Pregnancy and lactation: use only if potential benefit justifies potential risk.
  • Concomitant amino‑acid supplements: limit total intake to prevent metabolic overload.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Olimel N7e may interact with other medicines or therapies that affect amino‑acid metabolism or renal clearance.

Major Interactions (Avoid)

  • High‑dose protein supplements: may cause excessive nitrogen load and metabolic imbalance.
  • Renal dialysis sessions: can remove administered amino acids, reducing therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants such as valproate: may interfere with amino‑acid pathways.
  • Lithium therapy: potential for altered serum lithium levels.
  • Diuretics: may affect electrolyte balance when combined with amino‑acid supplementation.

Frequently Asked Questions

Olimel N7e is an oral powder that supplies a blend of essential amino acids. It is used to support nutritional rehabilitation in conditions such as protein‑energy malnutrition, post‑operative recovery, chronic kidney disease, and severe catabolic states like burns or trauma, where enhanced protein synthesis is required.

The formulation provides the building blocks needed for ribosomal protein synthesis. By delivering valine, leucine, isoleucine and other essential amino acids, it activates the mTOR pathway, promotes muscle protein accretion, restores nitrogen balance, and aids tissue repair during periods of increased metabolic demand.

The prescribed dose of Olimel N7e is determined by the treating clinician based on the patient’s age, weight, clinical condition, and nutritional requirements. Healthcare professionals calculate the appropriate amount and frequency to achieve the desired therapeutic effect.

Olimel N7e should only be used in pregnancy or while breastfeeding if the prescriber judges that the potential benefit outweighs any possible risk to the fetus or infant. Limited data are available, so careful clinical assessment is essential before initiating therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and the necessary import documentation.

Unlike generic protein powders that contain a mixture of proteins, Olimel N7e delivers a precise profile of free essential amino acids, allowing faster absorption and more direct stimulation of the mTOR pathway. This can be advantageous in clinical settings where rapid nitrogen delivery and specific amino‑acid ratios are needed.

Olimel N7e should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the powder from moisture, direct sunlight, and extreme heat to maintain stability and potency throughout its shelf life.

The product is supplied as a powdered formulation intended for oral use. It is typically reconstituted with water or mixed into a suitable beverage according to the prescriber’s instructions, and then ingested promptly to ensure optimal absorption.

The most serious risks include allergic reactions that may progress to anaphylaxis, metabolic acidosis in susceptible patients, and rare occurrences of hyperuricemia or hyperammonemia, particularly in individuals with severe renal or hepatic impairment. Immediate medical attention is required if any of these events occur.

Olimel N7e is contraindicated in patients with known hypersensitivity to any of its amino‑acid components, in those with severe renal or hepatic failure, and in individuals with inborn errors of metabolism affecting the supplied amino acids. Clinicians should also avoid use in patients receiving high‑dose protein supplements without proper monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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