Product image of Olimel N9 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Olimel N9

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Olimel N9 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N9, is a mixture of essential and non-essential amino acids presented as a sterile powder for intravenous use. It is intended for nutritional support in patients requiring parenteral amino acid supplementation.

GNH India supplies Olimel N9 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Manufacturer / TM Owner

Baxter Sa

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Indications & Clinical Uses

Olimel N9 provides a comprehensive amino acid profile for patients who need parenteral nutritional support. It is commonly used in the following clinical situations:

  • Post‑operative recovery: Helps to restore nitrogen balance and support tissue repair.
  • Critical illness or trauma: Supplies essential amino acids to mitigate catabolism.
  • Long‑term parenteral nutrition: Provides a balanced amino acid mixture for patients unable to receive enteral feeding.
  • Severe malnutrition: Contributes to rebuilding lean body mass.
  • Burn patients: Supports high protein turnover required for wound healing.

How It Works

  • Olimel N9 delivers a balanced blend of essential and non‑essential amino acids directly into the bloodstream, bypassing gastrointestinal absorption. The amino acids become substrates for protein synthesis, support nitrogen balance, and act as precursors for neurotransmitters and metabolic intermediates, thereby facilitating tissue repair and metabolic stability in patients receiving parenteral nutrition.

Side Effects

Adverse reactions to intravenous amino acid solutions are generally infrequent but can occur.

Common Side Effects

  • Mild infusion‑related erythema or warmth at the site.
  • Transient nausea or vomiting.
  • Slight increase in serum urea nitrogen.
  • Mild headache.
  • Low‑grade fever.
  • Temporary hyperglycaemia.

Serious or Rare Side Effects

  • Anaphylactic or severe hypersensitivity reaction.
  • Acute metabolic acidosis.
  • Hyperosmolar hyperglycaemic state.
  • Severe electrolyte disturbances (e.g., hyperkalemia, hypophosphatemia).
  • Renal impairment exacerbation.
  • Thrombophlebitis at the infusion site.

Precautions & Warnings

When using Olimel N9, clinicians should consider several safety measures:

  • Renal function: Assess baseline creatinine and adjust infusion rate in renal impairment.
  • Electrolyte balance: Monitor serum electrolytes regularly during therapy.
  • Metabolic status: Check acid‑base balance, especially in patients with respiratory or metabolic disorders.
  • Fluid overload: Evaluate total daily fluid volume to avoid volume excess.
  • Compatibility: Verify compatibility with other intravenous solutions before mixing.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Intravenous amino acid mixtures may interact with certain medications and clinical conditions.

Major Interactions (Avoid)

  • High‑dose insulin: May potentiate hypoglycaemia when combined with amino acid‑rich solutions.
  • Certain diuretics (loop, thiazide): Can exacerbate electrolyte shifts.
  • Acidifying agents: May increase risk of metabolic acidosis.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: Monitor coagulation parameters as amino acids can affect plasma protein binding.
  • Corticosteroids: May increase protein catabolism, requiring dose adjustments.
  • Parenteral lipid emulsions: Observe for compatibility and osmolarity changes.

Frequently Asked Questions

Olimel N9 is an intravenous amino acid formulation used to provide nutritional support for patients who cannot receive enteral feeding. It supplies essential and non‑essential amino acids to help maintain nitrogen balance, support tissue repair, and meet protein requirements in critical‑care, post‑operative, or long‑term parenteral nutrition settings.

The blend delivers a balanced set of amino acids directly into the bloodstream, where they serve as building blocks for protein synthesis, precursors for metabolic pathways, and regulators of nitrogen balance. By bypassing the gastrointestinal tract, the formulation quickly restores amino acid availability for cellular repair and metabolic functions.

The prescribed dose of Olimel N9 is determined by the treating physician based on the patient’s weight, clinical condition, and nutritional goals. Dosing is individualized and calculated to meet the required protein and nitrogen needs, typically expressed in grams of amino acids per kilogram of body weight per day.

Safety data for intravenous amino acid mixtures in pregnancy and lactation are limited. Use is generally reserved for situations where the benefit to the mother outweighs potential risks to the fetus or infant, and it should be prescribed by a specialist familiar with maternal‑fetal medicine.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Olimel N9 offers a comprehensive profile of ten amino acids in a single sterile powder, providing a balanced formulation comparable to other commercial amino acid blends. Differences may lie in individual amino‑acid concentrations, osmolarity, and compatibility with lipid emulsions, which clinicians consider when selecting a product for specific patient needs.

Store Olimel N9 at ambient temperature, protected from moisture and direct sunlight, in its original sealed container. Avoid freezing and ensure the product is reconstituted with the appropriate diluent under aseptic conditions before intravenous administration.

Olimel N9 is supplied as a sterile powder that must be reconstituted with a compatible diluent and administered intravenously, usually via a controlled infusion pump. The infusion rate is set by the prescribing clinician according to the patient’s nutritional plan and clinical status.

Serious risks include severe hypersensitivity reactions, metabolic acidosis, significant electrolyte disturbances, renal function worsening, and thrombophlebitis at the infusion site. Prompt monitoring and immediate medical intervention are essential if any of these events occur.

Patients with known hypersensitivity to any component of the formulation, uncontrolled severe electrolyte imbalances, or those for whom intravenous amino acid therapy is contraindicated should not receive Olimel N9. Clinical judgment is required to assess suitability on a case‑by‑case basis.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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