Product image of Olmeblo Hct (Olmesartan Medoxomil, Hydrochlorothiazide) supplied by GNH India

Olmeblo Hct

Active Ingredient:
Olmesartan Medoxomil, Hydrochlorothiazide
Origin:
EU

Olmeblo Hct (Olmesartan Medoxomil, Hydrochlorothiazide)

Olmesartan medoxomil, the active ingredient in Olmeblo Hct, is an angiotensin II receptor blocker combined with a thiazide diuretic presented as a tablet for oral use. It treats hypertension, often in patients who require additional blood pressure control beyond what a single agent can provide.

GNH India supplies Olmeblo Hct as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

G.L. Pharma Gmbh

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Indications & Clinical Uses

Olmeblo Hct is an antihypertensive medication that works within the renin‑angiotensin‑aldosterone system to lower elevated blood pressure.

  • Hypertension: helps achieve target blood pressure when monotherapy is insufficient.
  • Hypertensive patients with fluid retention: adds diuretic effect to improve blood pressure control.
  • High‑risk cardiovascular patients: contributes to overall risk reduction when combined with lifestyle measures.

How It Works

  • Olmesartan medoxomil selectively blocks the angiotensin II type 1 (AT1) receptor, preventing vasoconstriction and aldosterone release. Hydrochlorothiazide inhibits sodium‑chloride reabsorption in the distal convoluted tubule, promoting diuresis. The combined actions reduce peripheral vascular resistance and plasma volume, resulting in lowered systemic blood pressure.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Dizziness or light‑headedness
  • Headache
  • Fatigue
  • Increased urination
  • Electrolyte disturbances (e.g., low potassium)
  • Mild gastrointestinal discomfort

Serious or Rare Side Effects

  • Severe hypotension
  • Acute kidney injury
  • Hyperkalemia
  • Angio‑edema
  • Significant electrolyte imbalance (e.g., hyponatremia)
  • Liver function abnormalities

Precautions & Warnings

Before initiating Olmeblo Hct, consider the following precautions:

  • Renal function: assess baseline creatinine and eGFR.
  • Electrolytes: monitor potassium and sodium levels regularly.
  • Pregnancy: avoid use; drug is contraindicated in the second and third trimesters.
  • Concomitant NSAIDs: use with caution as they may reduce antihypertensive effect.
  • Gout: monitor uric acid as thiazides can precipitate attacks.

Store at ambient temperature: keep tablets in the original container, protect from moisture and light.

Avoid Interactions

Olmeblo Hct may interact with several drug classes; monitoring is advised.

Major Interactions (Avoid)

  • Lithium: increased risk of lithium toxicity.
  • Potassium‑sparing diuretics or supplements: risk of hyperkalemia.
  • ACE inhibitors or other ARBs: additive effect on blood pressure and kidney function.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may blunt antihypertensive response.
  • Antidiabetic agents: possible enhancement of hypoglycaemic effect.
  • Antimicrobials such as trimethoprim‑sulfamethoxazole: may affect potassium balance.

Frequently Asked Questions

Olmeblo Hct is a fixed‑dose combination of olmesartan medoxomil and hydrochlorothiazide indicated for the treatment of hypertension, particularly when blood pressure is not adequately controlled with a single‑agent therapy.

Olmesartan medoxomil is an angiotensin II receptor blocker that selectively inhibits the AT‑1 receptor, preventing angiotensin‑II‑induced vasoconstriction and aldosterone release, which helps lower systemic vascular resistance and blood pressure.

The dose of Olmeblo Hct is individualized by the prescribing clinician based on the patient’s blood pressure, renal function, and response to therapy. The prescriber determines the appropriate strength and dosing schedule.

Olmeblo Hct is contraindicated in pregnancy, especially during the second and third trimesters, because angiotensin‑II receptor blockers can cause fetal toxicity. Limited data are available for breastfeeding; therefore, use is generally not recommended without medical advice.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Olmeblo Hct combines an ARB with a thiazide diuretic, offering dual mechanisms—vascular relaxation and diuresis—in a single tablet. This can simplify regimens compared with separate prescriptions and may provide better blood‑pressure control than monotherapy with either component alone.

Store Olmeblo Hct tablets at ambient temperature, below 25 °C, in the original packaging. Protect them from moisture, excessive heat and direct sunlight to maintain potency.

Olmeblo Hct is taken orally, usually once daily, with or without food, as directed by the prescribing healthcare professional.

Serious risks include severe hypotension, acute kidney injury, hyperkalemia, angio‑edema and significant electrolyte disturbances. Patients should be monitored regularly for these events, especially when initiating therapy or adjusting doses.

Olmeblo Hct should be avoided in patients with known hypersensitivity to olmesartan, hydrochlorothiazide or any excipients, in pregnant women, and in individuals with severe renal impairment or uncontrolled electrolyte abnormalities.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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