Product image of Olmesartan 1 A Pharma (Olmesartan Medoxomil) supplied by GNH India

Olmesartan 1 A Pharma

Active Ingredient:
Olmesartan Medoxomil
Origin:
EU

Olmesartan 1 A Pharma (Olmesartan Medoxomil)

Olmesartan medoxil, the active ingredient in Olmesartan 1 A Pharma, is an Angiotensin drug presented as a tablet for oral use. It treats hypertension and is used in adult patients who require blood pressure control. GNH India supplies Olmesartan 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH India supplies Olmesartan 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

1 A Pharma Gmbh

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Indications & Clinical Uses

Olmesartan medoxil is indicated for the management of high blood pressure within the renin‑angiotensin‑aldosterone system pathway.

  • Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk.
  • Diabetic nephropathy (adjunct): helps slow progression of kidney damage when used with other antihypertensives.
  • Heart failure (adjunct): contributes to blood‑pressure control as part of combination therapy.

How It Works

  • Olmesartan medoxil is a selective antagonist of the angiotensin II type 1 (AT1) receptor. By blocking this receptor, it prevents angiotensin II‑mediated vasoconstriction and aldosterone secretion, leading to vasodilation, reduced peripheral resistance, and decreased blood pressure.

Side Effects

Olmesartan medoxil may cause a range of adverse reactions. Monitoring for side effects is part of routine clinical care.

Common Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Nasal congestion
  • Diarrhea

Serious or Rare Side Effects

  • Angio‑edema
  • Severe hypotension
  • Acute kidney injury
  • Hyperkalemia
  • Liver enzyme elevation

Precautions & Warnings

When prescribing Olmesartan medoxil, clinicians should consider several safety aspects.

  • Monitor blood pressure: ensure adequate control without excessive lowering.
  • Assess renal function: adjust use in patients with impaired kidneys.
  • Check electrolytes: watch for potassium abnormalities.
  • Avoid in pregnancy: drug is contraindicated due to fetal risk.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Olmesartan medoxil can interact with several other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Potassium‑sparing diuretics: may cause dangerous hyper‑kalemia.
  • Aliskiren (in diabetics): heightened risk of renal impairment.
  • NSAIDs (high dose): can blunt antihypertensive effect and affect kidney function.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: combined use may increase risk of hypotension and renal dysfunction.
  • Lithium: may raise lithium levels, requiring serum monitoring.
  • Thiazide diuretics: may enhance potassium loss, needing electrolyte checks.

Frequently Asked Questions

Olmesartan 1 A Pharma contains olmesartan medoxil, an angiotensin II receptor blocker that is prescribed to lower high blood pressure. It helps manage hypertension and may be used as part of combination therapy to reduce the risk of cardiovascular events in adults.

Olmesartan medoxil selectively blocks the AT1 receptor for angiotensin II, preventing the hormone from causing blood vessels to narrow and reducing aldosterone release. This results in vasodilation, lower peripheral resistance, and a decrease in blood pressure.

The appropriate dose is determined by the prescribing clinician based on the patient’s blood pressure, response to therapy, and any co‑existing medical conditions. Dosage adjustments are made during follow‑up visits.

Olmesartan is contraindicated in pregnancy because it can cause fetal toxicity and injury. Limited data are available for breastfeeding, and the drug is generally not recommended unless the benefit outweighs potential risk.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Olmesartan belongs to the angiotensin II receptor blocker (ARB) class, which unlike ACE inhibitors does not typically cause a dry cough. It offers similar blood‑pressure‑lowering efficacy to other ARBs and is often chosen for patients who are intolerant to ACE inhibitors.

Store the tablets below 25 °C in their original container, protecting them from moisture and direct sunlight. Do not expose the product to excessive heat or humidity to maintain potency.

Olmesartan 1 A Pharma is taken orally, usually once daily, with or without food. Patients should follow the prescribing clinician’s instructions regarding timing and whether to swallow the tablet whole.

Serious adverse events include angio‑edema, severe hypotension, acute kidney injury, and hyper‑kalemia. Prompt medical attention is required if swelling of the face, lips or throat, sudden dizziness, or significant changes in kidney function occur.

Olmesartan should not be used by individuals who are pregnant, have known hypersensitivity to olmesartan or any ARB component, or have severe renal artery stenosis. Clinicians should also exercise caution in patients with advanced kidney disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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