Product image of Olmesartan/Amlodipine Ab (Olmesartan Medoxomil, Amlodipine) supplied by GNH India

Olmesartan/Amlodipine Ab

Active Ingredient:
Olmesartan Medoxomil, Amlodipine
Origin:
EU

Olmesartan/Amlodipine Ab (Olmesartan Medoxomil, Amlodipine)

Olmesartan medoxil, the active ingredient in Olmesartan/Amlodipine Ab, is an angiotensin II receptor blocker (ARB) presented as a tablet for oral use. It treats hypertension, often in combination with a calcium‑channel blocker, and is intended for adult patients. GNH India supplies Olmesartan/Amlodipine Ab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH India supplies Olmesartan/Amlodipine Ab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Aurobindo N.V.

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Indications & Clinical Uses

Olmesartan/Amlodipine Ab is indicated for hypertension management, targeting the renin‑angiotensin system and vascular smooth‑muscle tone.

  • Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk.
  • Hypertension with high peripheral resistance: improves arterial compliance and flow.
  • Hypertension in patients requiring combination therapy: provides additive blood‑pressure control when monotherapy is insufficient.

How It Works

  • Olmesartan medoxil selectively blocks the angiotensin II type 1 (AT1) receptor, preventing vasoconstriction and aldosterone release. Amlodipine, a dihydropyridine calcium‑channel blocker, inhibits calcium influx into vascular smooth‑muscle cells, causing dose‑dependent arterial dilation. Together they produce complementary reductions in systemic vascular resistance and blood pressure.

Side Effects

Common Side Effects

  • Peripheral edema edema
  • Headache
  • Dizziness
  • Flushing
  • Fatigue
  • Nausea

Serious or Rare Side Effects

  • Angio‑immun  
  • Hepatotoxic  
  • Severe hypotension
  • Myocardial infarction  
  • Acute kidney injury  
  • Life‑threatening arrhythmias

Precautions & Warnings

Olmesartan/Amlodipine Ab should be used cautiously.

  • Renal impairment: monitor renal function and electrolytes.
  • Hepatic impairment: dose adjustment may be needed.
  • Hyperkalemia: check serum potassium regularly.\n- Pregnancy   
  • Cardiovascular  
  • Store at  

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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