Product image of Olmesartán Cinfa (Olmesartan Medoxomil) supplied by GNH India

Olmesartán Cinfa

Active Ingredient:
Olmesartan Medoxomil
Origin:
EU

Olmesartán Cinfa (Olmesartan Medoxomil)

Olmesartan medoxyl, the active ingredient in Olmesartán Cinfa, is a angiotensin II receptor blocker presented as a tablet for oral use. It is indicated for the management of hypertension in adults. GNH India supplies Olmesartán Cinfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH India supplies Olmesartán Cinfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

Olmesartan medoxyl is used to treat high blood pressure by targeting the renin‑angiotensin system.

  • Hypertension: helps lower systolic and diastolic blood pressure to reduce cardiovascular risk.
  • Diabetic nephropathy: slows progression of kidney damage associated with diabetes.
  • Heart failure: used as part of combination therapy to improve cardiac output and symptoms.

How It Works

  • Olmesartan medoxyl selectively blocks the binding of angiotensin II to the AT1 receptor on vascular smooth‑muscle cells and adrenal tissue. This inhibition prevents vasoconstriction and aldosterone release, leading to reduced peripheral resistance, lower blood pressure, and decreased sodium and water retention.

Side Effects

Olmesartan medoxyl may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Nasal congestion
  • Diarrhea
  • Upper respiratory tract infection

Serious or Rare Side Effects

  • Angio‑edema
  • Hyperkalemia
  • Acute kidney injury
  • Severe hypotension
  • Liver enzyme elevation
  • Allergic skin reactions

Precautions & Warnings

When prescribing Olmesartan medoxyl, clinicians should consider several safety aspects.

  • Renal function: assess baseline kidney function and monitor periodically.
  • Electrolytes: check serum potassium, especially if combined with potassium‑sparing diuretics.
  • Pregnancy: avoid use during the second and third trimesters due to fetal toxicity.
  • Elderly patients: start at lower doses and monitor blood pressure response.
  • Drug interactions: review concomitant medications for additive hypotensive effects.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Olmesartan medoxyl can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Aliskiren: combined use in diabetic patients may increase risk of renal impairment.
  • Potassium‑sparing diuretics: may cause dangerous hyper‑kalemia.
  • NSAIDs: can blunt antihypertensive effect and affect renal function.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: concurrent use may increase risk of hypotension and renal dysfunction.
  • Lithium: may raise lithium levels, necessitating serum monitoring.
  • Thiazide diuretics: may enhance antihypertensive effect, requiring blood pressure checks.

Frequently Asked Questions

Olmesartán Cinfa contains olmesartan medoxyl, an angiotensin II receptor blocker that is prescribed to lower high blood pressure and reduce the risk of cardiovascular events in adults with hypertension.

Olmesartan medoxyl selectively blocks AT1 receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release. This leads to relaxed blood vessels, reduced fluid retention, and lower blood pressure.

The appropriate dose is determined by the prescribing clinician based on the patient’s blood pressure, renal function, and overall health profile. Dosage adjustments are made during treatment as needed.

Olmesartan is contraindicated in the second and third trimesters of pregnancy because of potential fetal toxicity. Limited data exist for breastfeeding; clinicians usually advise against use unless the benefit outweighs potential risk.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Olmesartan belongs to the ARB class, offering blood‑pressure control comparable to other ARBs and ACE inhibitors but with a lower incidence of cough. It is often chosen when patients cannot tolerate ACE‑inhibitor‑related side effects.

Store the tablets at temperatures below 25 °C in their original container, protecting them from moisture, heat and direct sunlight to maintain potency throughout the shelf‑life.

Olmesartán Cinfa is taken orally, usually once daily, with or without food. Patients should follow the prescribing physician’s instructions regarding timing and any accompanying dietary considerations.

Serious adverse events, though rare, include angio‑edema, severe hypotension, acute kidney injury and hyper‑kalemia. Prompt medical attention is required if any of these symptoms develop.

Individuals with known hypersensitivity to olmesartan or any tablet excipients, pregnant women in their second or third trimester, and patients with severe renal artery stenosis should avoid this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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