Product image of Olmesartan Medoxomil/ Amlodipine Zentiva (Olmesartan Medoxomil, Amlodipine) supplied by GNH India

Olmesartan Medoxomil/ Amlodipine Zentiva

Active Ingredient:
Olmesartan Medoxomil, Amlodipine
Origin:
EU

Olmesartan Medoxomil/ Amlodipine Zentiva (Olmesartan Medoxomil, Amlodipine)

Olmesartan medoxil, the active ingredient in Olmesartan Medoxomil/ Amlodipine Zentiva, is a angiotensin II receptor blocker presented as a tablet for oral use. It treats hypertension, often in combination with a calcium‑channel blocker, and is intended for adult patients. GNH India supplies Olmesartan Medoxomil/ Amlodipine Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH India supplies Olmesartan Medoxomil/ Amlodipine Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Zentiva, K.S.

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Indications & Clinical Uses

Olmesartan Medoxil/Amlodipine is indicated for hypertension management, targeting the renin‑angiotensin system and vascular smooth‑muscle tone.

  • Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk.
  • Hypertension with high vascular resistance: provides additional vasodilation through calcium‑channel blockade.
  • Hypertension in patients who require combination therapy: simplifies treatment by combining two mechanisms of action.
  • Hypertension in elderly patients: offers effective blood pressure control with a single pill.
  • Hypertension resistant to monotherapy: improves control when a single agent is insufficient.
  • Hypertension with accompanying edema risk: amlododipine component mitigates fluid retention.

How It Works

  • Olmesartan medoxil is a selective angiotensin II type 1 (AT1) receptor antagonist that blocks the vasoconstrictive effects of angiotensin II, leading to vasodilation and reduced aldosterone‑driven sodium retention. Amlodipine is a dihydropyridine calcium‑channel blocker that inhibits calcium influx into vascular smooth‑muscle cells, causing arterial relaxation  ​​  ​   ​   ​  ​  ​  ​  ​   ​    ​   ​   ​    
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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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