Product image of Olmesartan Medoxomilo + Hidroclorotiazida Viatris (Olmesartan Medoxomil, Hydrochlorothiazide) supplied by GNH India

Olmesartan Medoxomilo + Hidroclorotiazida Viatris

Active Ingredient:
Olmesartan Medoxomil, Hydrochlorothiazide
Origin:
EU

Olmesartan Medoxomilo + Hidroclorotiazida Viatris (Olmesartan Medoxomil, Hydrochlorothiazide)

Olmesartan medoxil, the active ingredient in Olmesartan Medoxomilo + Hidroclorotiazida Viatris, is an angiotensin II receptor blocker presented as a oral tablet for hypertension management in adults. It combines olmesartan medoxil with hydrochlorothiazide to lower blood pressure through dual mechanisms.

GNH India supplies Olmesartan Medoxomilo + Hidroclorotiazida Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Viatris Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Olmesartan medoxil/hydrochlorothiazide is indicated for cardiovascular conditions that involve elevated blood pressure and fluid retention.

  • Hypertension: improves blood pressure control when monotherapy is insufficient.
  • Congestive heart failure: assists in reducing preload and afterload, supporting symptom management.
  • Diabetic nephropathy: helps protect renal function by controlling systemic hypertension.
  • Post‑myocardial infarction: contributes to secondary prevention by maintaining target blood pressure levels.

How It Works

  • Olmesartan medoxil selectively blocks the AT1 subtype of angiotensin II receptors, preventing vasoconstriction and aldosterone release. Hydrochlorothiazide inhibits sodium‑chloride reabsorption in the distal convoluted tubule, promoting diuresis. The combination yields additive blood‑pressure‑lowering effects through vascular relaxation and reduced plasma volume.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Dizziness or light‑headedness
  • Headache
  • Fatigue
  • Increased urination
  • Electrolyte disturbances (e.g., low potassium)
  • Mild gastrointestinal discomfort

Serious or Rare Side Effects

  • Severe hypotension
  • Acute kidney injury
  • Hyperkalemia
  • Angio‑edema
  • Liver function abnormalities
  • Blood cell disorders such as agranulocytosis

Precautions & Warnings

Before initiating therapy, consider the following safety measures:

  • Renal function: assess baseline creatinine and eGFR.
  • Electrolyte balance: monitor potassium and sodium levels regularly.
  • Pregnancy: avoid use; drug is contraindicated in the second and third trimesters.
  • Concomitant NSAIDs: use with caution due to increased risk of renal impairment.
  • Gout: monitor uric acid as thiazides may precipitate attacks.
  • Store at below 25°C: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Olmesartan medoxil/hydrochlorothiazide may interact with several drug classes. Review the following:

Major Interactions (Avoid)

  • Aliskiren: combined use can cause excessive potassium loss and renal dysfunction.
  • Potassium‑sparing diuretics or supplements: risk of hyper‑kalemia.
  • Lithium: increased lithium levels may lead to toxicity.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may blunt antihypertensive effect and affect renal function.
  • ACE inhibitors or ARBs: additive potassium elevation.
  • Antidiabetic agents: may require dose adjustment due to enhanced glucose lowering.

Frequently Asked Questions

Olmesartan Medoxomilo + Hidroclorotiazida is a fixed‑dose combination of olmesartan medoxil and hydrochlorothiazide indicated for the treatment of hypertension, often when blood pressure is not adequately controlled with a single agent. It may also be used in patients with associated conditions such as heart failure or diabetic kidney disease, as part of a broader cardiovascular risk‑reduction strategy.

Olmesartan medoxil is an angiotensin II receptor blocker that selectively inhibits AT‑1 receptors, preventing angiotensin‑II‑mediated vasoconstriction and aldosterone secretion. This leads to relaxation of blood vessels and reduced sodium‑water retention, helping to lower systemic blood pressure.

The appropriate dose is determined by the prescribing clinician based on the patient’s blood pressure, renal function, and overall clinical profile. Dosage adjustments are made according to therapeutic response and tolerability, following local prescribing guidelines.

Olmesartan Medoxomilo + Hidroclorotiazida is contraindicated in pregnancy, particularly in the second and third trimesters, because it can cause fetal toxicity. Breastfeeding is not recommended unless the benefits outweigh potential risks, and this decision should be made by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with monotherapy using either an ARB or a thiazide diuretic, the olmesartan‑hydrochlorothiazide combo offers additive blood‑pressure reduction, often achieving target levels with a single tablet. It may be preferred over separate pills for adherence, but clinicians consider individual patient factors when selecting alternatives such as ACE‑inhibitor‑diuretic combos or calcium‑channel blocker‑based regimens.

Store the tablets at temperatures below 25 °C in their original container, protecting them from moisture, heat and direct sunlight. Do not refrigerate or freeze the product.

The medication is taken orally, usually once daily, with or without food. Patients should follow the prescribing clinician’s instructions regarding timing and whether the tablet should be swallowed whole or can be divided, if permitted.

Serious adverse events include severe hypotension, acute kidney injury, hyper‑kalemia, angio‑edema and liver function abnormalities. Patients should seek immediate medical attention if they experience symptoms such as sudden dizziness, swelling of the face or throat, or marked changes in urine output.

The product should be avoided in patients with known hypersensitivity to olmesartan, hydrochlorothiazide or any excipients, in pregnant women, and in individuals with severe renal impairment or electrolyte disturbances that could be worsened by a thiazide diuretic.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.