Product image of Olmesartan Vir (Olmesartan Medoxomil) supplied by GNH India

Olmesartan Vir

Active Ingredient:
Olmesartan Medoxomil
Origin:
EU

Olmesartan Vir (Olmesartan Medoxomil)

Olmesartan Medoxomil, the active ingredient in Olmesartan Vir, is an angiotensin II receptor blocker presented as an oral tablet for oral use. It lowers elevated blood pressure in adults diagnosed with hypertension. GNH India supplies Olmesartan Vir as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Industria Química Y Farmaceútica Vir, S.A.

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Indications & Clinical Uses

  • Olmesartan Vir is an antihypertensive agent that acts on the renin‑angiotensin system to control high blood pressure.
  • Hypertension: reduces systolic and diastolic blood pressure in adults with essential hypertension.

How It Works

  • Olmesartan Medoxomil is a selective antagonist of the angiotensin II type 1 (AT1) receptor. By blocking AT1 receptors, it prevents angiotensin II‑mediated vasoconstriction and aldosterone secretion, leading to vasodilation, reduced sodium and water retention, and ultimately a decrease in systemic blood pressure.

Side Effects

Common Side Effects

  • Dizziness or light‑headedness
  • Headache
  • Fatigue or tiredness
  • Upper respiratory tract infection symptoms
  • Diarrhoea or abdominal discomfort
  • Back pain

Serious or Rare Side Effects

  • Angioedema (swelling of face, lips, tongue)
  • Hyperkalaemia (elevated blood potassium)
  • Acute kidney injury or worsening renal function
  • Severe hypotension
  • Hepatic enzyme elevations
  • Myocardial infarction (rare)

Precautions & Warnings

Olmesartan Vir should be used with caution in specific clinical situations.

  • Pregnancy: Category D – avoid use during pregnancy due to fetal risk.
  • Renal impairment: monitor renal function and adjust therapy as needed.
  • Hepatic impairment: use with caution; monitor liver enzymes.
  • Concomitant potassium‑sparing agents or supplements: watch for hyperkalaemia.
  • Dual blockade with ACE inhibitors or other ARBs: increase risk of renal dysfunction and hyperkalaemia.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Olmesartan Vir may interact with several medicines.

Major Interactions (Avoid)

  • Aliskiren in patients with diabetes: increased risk of renal impairment.
  • Potassium supplements or potassium‑sparing diuretics: risk of hyperkalaemia.
  • ACE inhibitors or other ARBs: additive effect on potassium and renal function.
  • Lithium: may increase lithium serum concentrations.
  • High dose NSAIDs: can reduce antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely)

  • Thiazide diuretics: may enhance antihypertensive effect, monitor blood pressure.
  • CYP450 inhibitors (e.g., ketoconazole): may modestly increase olmesartan levels.
  • Other antihypertensives (beta‑blockers, calcium channel blockers): additive blood pressure lowering, watch for hypotension.
  • Diuretics that cause volume depletion: monitor renal function and electrolytes.
  • Antidiabetic drugs: blood pressure reduction may affect glucose control.

Frequently Asked Questions

Olmesartan Vir contains olmesartan medoxomil, an angiotensin II receptor blocker prescribed to lower high blood pressure in adults with hypertension. By reducing vascular resistance, it helps prevent complications such as stroke, heart attack, and kidney damage associated with uncontrolled hypertension.

Olmesartan medoxomil selectively blocks the AT1 subtype of angiotensin II receptors. This inhibition prevents angiotensin II‑induced vasoconstriction and aldosterone release, leading to relaxed blood vessels, reduced sodium and water retention, and a subsequent fall in systemic blood pressure.

The appropriate dose of Olmesartan Vir is determined by a qualified prescriber based on the individual’s blood pressure, response to therapy, and clinical condition. Dosage adjustments are made according to therapeutic goals and tolerability.

Olmesartan Vir is classified as Pregnancy Category D, indicating evidence of fetal risk and it should be avoided in pregnancy. Safety during breastfeeding has not been established, so the drug is generally not recommended for nursing mothers unless the benefit outweighs the risk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Olmesartan Vir belongs to the ARB class, which offers blood‑pressure control similar to ACE inhibitors but with a lower incidence of cough and angioedema. Compared with calcium‑channel blockers, ARBs act on the renin‑angiotensin system rather than directly relaxing vascular smooth muscle.

Olmesartan Vir should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Olmesartan Vir is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional.

Serious risks include angioedema, which can cause swelling of the face, lips, tongue, or throat, and hyperkalaemia, a potentially dangerous rise in blood potassium levels. Acute kidney injury may also occur, especially when combined with other nephrotoxic agents.

Olmesartan Vir should not be used by individuals with known hypersensitivity to olmesartan or any component of the formulation, pregnant women, or patients with severe hepatic impairment. Caution is also advised for those with bilateral renal artery stenosis or significant renal dysfunction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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