Product image of Olopatadină Rompharm (Olopatadine) supplied by GNH India

Olopatadină Rompharm

Active Ingredient:
Olopatadine
Origin:
EU

Olopatadină Rompharm (Olopatadine)

Olopatadine, the active ingredient in Olopatadină Rompharm, is an antihistamine presented as a 0.1% ophthalmic solution for topical ocular use. It treats allergic eye inflammation and related symptoms in patients with seasonal or perennial allergies.
GNH India supplies Olopatadină Rompharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

S.C. Rompharm Company S.R.L.

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Indications & Clinical Uses

Olopatadine is an antihistamine that acts on ocular allergic pathways to relieve inflammation and itching.

  • Allergic conjunctivitis: reduces eye redness, itching and tearing caused by allergens.
  • Vernal keratoconjunctivitis: helps control chronic inflammation in seasonal eye allergy.
  • Seasonal allergic rhinitis (when supplied as oral form): alleviates nasal itching and sneezing associated with pollen exposure.

How It Works

  • Olopatadine selectively antagonizes histamine H1 receptors on conjunctival mast cells, preventing histamine‑mediated vasodilation and increased vascular permeability. It also stabilises mast cells, inhibiting the release of inflammatory mediators such as leukotrienes and cytokines, thereby reducing ocular itching, redness and swelling.

Side Effects

Olopatadine is generally well tolerated, but ocular and systemic reactions can occur.

Common Side Effects

  • Burning or stinging sensation in the eye.
  • Transient blurred vision.
  • Mild headache.
  • Dry eye sensation.
  • Unpleasant taste after administration.
  • Redness of the eyelid margin.

Serious or Rare Side Effects

  • Corneal edema or ulceration.
  • Severe allergic reaction (anaphylaxis).
  • Increased intra‑ocular pressure.
  • Persistent eye irritation or infection.
  • Vision loss.
  • Systemic hypersensitivity (rash, swelling).

Precautions & Warnings

Before using Olopatadină Rompharm, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: use only if the benefit outweighs potential risk.
  • Contact lens wearers: remove lenses prior to instillation and wait at least 15 minutes before reinserting.
  • Known hypersensitivity: avoid if allergic to olopatadine or any excipient.
  • Glaucoma patients: monitor intra‑ocular pressure regularly.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Olopatadine may interact with other medications; review the following categories.

Major Interactions (Avoid)

  • Concomitant use of other topical antihistamines: may increase local irritation.
  • Systemic MAO inhibitors: theoretical risk of additive antihistaminic effects.
  • CYP3A4 inhibitors (e.g., ketoconazole): could raise systemic exposure in oral formulations.

Moderate Interactions (Monitor Closely):\n- Anticholinergic eye drops: may exacerbate dry‑eye symptoms.

  • Topical ophthalmic NSAIDs: potential for increased ocular irritation.
  • Systemic sedating antihistamines: may enhance drowsiness if oral olopatadine is used.

Frequently Asked Questions

Olopatadină Rompharm contains olopatadine, an antihistamine indicated for allergic conjunctivitis, vernal keratoconjunctivitis, and, when supplied in oral form, seasonal allergic rhinitis. It helps relieve eye itching, redness, and tearing caused by allergen exposure.

Olopatadine blocks histamine H1 receptors on mast cells in the eye, preventing histamine‑induced vasodilation and vascular leakage. It also stabilises mast cells, reducing the release of other inflammatory mediators, which together diminish itching, redness, and swelling.

The specific dose and frequency are determined by the prescribing clinician based on the patient’s age, severity of symptoms, and formulation (eye drops or oral tablets). Patients should follow the prescriber’s instructions and the product label.

Safety data are limited. Women who are pregnant or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Olopatadină Rompharm. The prescriber will decide if the medication is appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Olopatadine offers both H1‑receptor antagonism and mast‑cell stabilisation, providing rapid symptom relief and longer‑lasting control compared with many first‑generation antihistamine drops that lack mast‑cell stabilising activity. Clinical choice depends on efficacy, tolerability and patient preference.

Store Olopatadină Rompharm at room temperature, below 25 °C, in the original packaging. Protect the container from direct sunlight, moisture and extreme temperature fluctuations to maintain product stability.

For the ophthalmic solution, instil the prescribed number of drops into the affected eye(s) as directed, typically once or twice daily. If an oral formulation is supplied, the tablet should be swallowed with water according to the prescriber’s instructions.

Serious adverse events, though rare, include corneal edema, severe allergic reactions such as anaphylaxis, and increased intra‑ocular pressure. Patients should seek immediate medical attention if they experience sudden vision changes, severe eye pain, or signs of systemic hypersensitivity.

Individuals with a known hypersensitivity to olopatadine or any excipients in the formulation should avoid the product. Caution is also advised for patients with uncontrolled glaucoma, severe ocular infections, or those who cannot safely remove contact lenses before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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