Product image of Olvorin 100mg (Leucovorin Calcium ) 100mg/10ml Vials supplied by GNH India

Olvorin 100mg

Active Ingredient:
Leucovorin Calcium
Form:
Vials
Brand:
Olvorin 100mg
Origin:
India

Olvorin 100mg (Leucovorin Calcium Vials) 100mg/10ml

Olvorin 100mg is a leucovorin calcium injection used to reduce toxic effects of folate antagonists like methotrexate. This 100mg/10ml vial supports folate-dependent metabolic processes. Ideal for clinics and hospitals managing chemotherapy adjuncts. Short-term ambient storage maintains potency for reliable use.

Strength

100mg/10ml

Pack Size

1s

Storage

Ambient

Manufacturer / TM Owner

Beta Drugs Ltd

1
Pack/s
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Indications & Clinical Uses

  • Olvorin 100mg provides folinic acid to counteract folate antagonist toxicity during high-dose methotrexate therapy. It supports DNA synthesis and cell repair in rapidly dividing tissues. Clinicians use it to rescue normal cells while preserving chemotherapy efficacy. Also used to treat folate deficiency in certain malabsorption conditions.

Side Effects

  • After administration, leucovorin calcium is converted to active folate coenzymes that support cellular metabolism. Patients may experience improved energy levels as folate-dependent pathways resume function. Some report reduced nausea when used as part of methotrexate rescue protocols.

Precautions & Warnings

  • Store Olvorin 100mg vials at room temperature away from moisture and light. Protect from freezing and excessive heat. Use within labeled expiration date for optimal potency. Discard unused portion after opening to maintain sterility. Keep out of reach of children and pets.

Avoid Interactions

  • Leucovorin may reduce the effects of certain antiepileptic drugs like phenobarbital and phenytoin. Combining with fluorouracil can enhance its cytotoxic effects in some chemotherapy regimens. Alcohol may diminish folate absorption when used concurrently. Always disclose all medications to healthcare providers before use.

Frequently Asked Questions

It is primarily used to counteract folate antagonist toxicity, such as from methotrexate chemotherapy.

Store at room temperature, away from moisture and light, and use before the expiration date.

It may interact with certain drugs; consult a healthcare provider before combining therapies.

It is typically administered in clinical settings due to the need for sterile handling and monitoring.

Published by GNH India Pharmaceuticals Limited

Last updated:

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