Product image of Olydex (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Olydex

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Olydex (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride, the active ingredient in Olydex, is a decongestant presented as a nasal formulation for topical nasal use. It relieves nasal congestion associated with common colds, sinusitis, and allergic rhinitis in adults and children. GNH India supplies Olydex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Olydex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mcneil Healthcare (Ireland) Limited

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Indications & Clinical Uses

Olydex combines the decongestant action of xylometazoline with the mucosal healing properties of dexpanthenol, acting on nasal passages to reduce swelling and improve airflow.

  • Common cold: reduces nasal blockage and improves breathing.
  • Acute sinusitis: eases congestion and facilitates sinus drainage.
  • Allergic rhinitis: diminishes nasal swelling and discharge.
  • Nasal irritation: soothes irritated nasal mucosa and supports recovery.

How It Works

  • Xylometazoline hydrochloride acts as an alpha‑adrenergic agonist, causing vasoconstriction of the nasal mucosal blood vessels, which reduces edema and congestion. Dexpanthenol is converted to pantothenic acid in the nasal tissues, promoting cellular repair and maintaining mucosal integrity.

Side Effects

Side effects are generally mild and related to local nasal irritation.

Common Side Effects

  • Burning sensation in the nose.
  • Stinging or itching itching.
  • Mild dryness of the nasal mucosa.
  • Sneezing.
  • Transient headache.

Serious or Rare Side Effects

  • Persistent nasal irritation or ulceration.
  • Severe allergic reaction (anaphylaxis, rash, swelling).
  • Nasal bleeding (epistaxis) that does not stop.
  • Vision changes or eye pain.
  • Rebound congestion with prolonged use over 5‑7 days.

Precautions & Warnings

Before using Olydex, consider the following precautions:

  • Age restriction: Not recommended for children under 6 years without medical advice.
  • Duration of use: Limit to 5‑7 days to avoid rebound congestion.
  • Pre‑existing conditions: Use cautiously if you have hypertension, heart disease or diabetes.
  • Pregnancy and lactation: Consult the health‑care provider before use.
  • Drug interactions: Discuss any concurrent nasal or systemic decongestants with your physician.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Olydex may interact with other medications, especially those affecting vascular tone.

Major Interactions (Avoid)

  • Mono‑universal . 

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Frequently Asked Questions

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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