Product image of Olydex (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Olydex

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Olydex (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride, the active ingredient in Olydex, is a decongestant presented as a nasal spray for topical nasal use. It relieves nasal congestion associated with the common cold, allergic rhinitis and sinusitis in adults and children. Dexpanthenol, also present in Olydex, supports mucosal healing and moisturisation.

GNH India supplies Olydex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mcneil Healthcare (Ireland) Limited

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Indications & Clinical Uses

Olydex, containing xylometazoline hydrochloride, acts on nasal mucosal blood vessels to reduce congestion.

  • Common cold: alleviates nasal blockage and improves breathing.
  • Allergic rhinitis: reduces congestion caused by seasonal or perennial allergens.
  • Sinusitis: helps clear nasal passages and eases pressure.
  • Nasal congestion due to upper respiratory infections: provides rapid decongestion.
  • Post‑operative nasal swelling: assists in maintaining airway patency.

How It Works

  • Xylometazoline hydrochloride is a selective α‑adrenergic agonist that induces vasoconstriction of the arterioles in the nasal mucosa, decreasing edema and secretions. Dexpanthenol, a provitamin B5 derivative, promotes epithelial repair and enhances mucosal hydration, supporting the overall decongestant effect and comfort of the nasal lining.

Side Effects

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal mucosa.
  • Sneezing or mild itching.
  • Headache.
  • Altered taste perception.
  • Mild epistaxis.

Serious or Rare Side Effects

  • Severe nasal bleeding.
  • Allergic reactions such as rash, swelling or urticaria.
  • Nasal ulceration or perforation with prolonged use.
  • Hypertension or tachycardia in susceptible individuals.
  • Vision disturbances (rare).

Precautions & Warnings

Before using Olydex, consider the following precautions:

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: use only if advised by a physician.
  • Age restrictions: not recommended for children under 6 years without medical guidance.
  • Cardiovascular disease: use with caution in patients with hypertension or heart conditions.
  • Concurrent nasal surgery or trauma: avoid use until cleared by a specialist.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Olydex may interact with other medications. Review the following:

Major Interactions (Avoid)

  • Oral sympathomimetic decongestants (e.g., pseudoephedrine): additive vasoconstrictive effects may increase blood pressure.
  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive episodes.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may blunt the decongestant response.
  • Antihypertensive agents: monitor blood pressure for possible elevation.
  • Nasal corticosteroids: assess for increased local irritation.

Frequently Asked Questions

Olydex is an over‑the‑counter nasal spray that contains xylometazoline hydrochloride and dexpanthenol. It is used to relieve nasal congestion caused by the common cold, allergic rhinitis, sinusitis and other upper‑respiratory tract conditions by narrowing swollen blood vessels in the nasal passages.

Xylometazoline Hydrochloride acts as a selective alpha‑adrenergic agonist. By stimulating alpha receptors on the nasal mucosal blood vessels, it causes vasoconstriction, which reduces swelling and excess mucus, leading to improved airflow through the nose.

The appropriate dose of Olydex is determined by the prescribing healthcare professional based on the patient’s age, condition and response. Typically, a few sprays per nostril are used, but the exact regimen should follow the prescriber’s instructions.

Pregnant or breastfeeding individuals should only use Olydex after consulting a qualified healthcare provider. While limited data exist, the benefits and potential risks need to be evaluated on a case‑by‑case basis.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Olydex combines xylometazoline, a fast‑acting vasoconstrictor, with dexpanthenol, which supports mucosal healing. Compared with single‑ingredient decongestants, this formulation may offer added comfort and reduced irritation, though efficacy and safety remain comparable when used as directed.

Olydex should be stored at room temperature, below 25 °C, in its original packaging. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and avoid freezing the product.

Olydex is applied as a nasal spray. The user tilts the head slightly forward, inserts the nozzle into one nostril, and sprays the prescribed number of actuations while breathing in gently. The same procedure is repeated for the other nostril if required.

Serious risks, though rare, include severe nasal bleeding, allergic reactions such as rash or swelling, and nasal ulceration or perforation with prolonged use. Patients should discontinue use and seek medical attention if any of these symptoms occur.

Olydex should be avoided by individuals with known hypersensitivity to xylometazoline, dexpanthenol or any excipients, children under six years of age unless directed by a physician, and patients with severe hypertension or recent nasal surgery without medical approval.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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