Product image of Olynth Combo (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Olynth Combo

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Olynth Combo (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline hydrochloride, the active ingredient in Olynth Combo, is a decongestant presented as a nasal spray for topical use. It relieves nasal congestion associated with colds, sinusitis and allergic rhinitis in adults and children. GNH India supplies Olynth Combo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Olynth Combo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mcneil Healthcare (Ireland) Limited

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Indications & Clinical Uses

Olynth Combo combines both a nasal decongestant and a skin‑protective agent, acting on the nasal mucosa and superficial skin lesions.

  • Nasal congestion: Reduces swelling of nasal mucosa to improve airflow during common cold or allergic rhinitis.
  • Sinusitis: Helps alleviate blocked sinuses by shrinking swollen blood vessels in the nasal passages.
  • Minor skin irritation: Dexamethasone provides a protective barrier that supports healing of irritated skin around the nostrils.
  • Post‑procedural care: Assists in keeping nasal passages moist and clear after nasal instrumentation.
  • Allergic rhinitis: Controls nasal blockage associated with seasonal allergies.

How It Works

  • Xylometazoline hydrochloride is an imidazoline‑type alpha‑adrenergic agonist that selectively stimulates alpha‑2 receptors in the nasal mucosal blood vessels, causing vasoconstriction and reduced edema. Dexpanthenol is converted to pantothenic acid in the skin, promoting cellular proliferation and repair, which supports mucosal healing and barrier function.

Side Effects

Adverse reactions are generally mild and related to local irritation.

Common Side Effects

  • Burning sensation: Mild burning or stinging at the application site.
  • Nasal dryness: Dryness or crusting of the nasal mucosa.
  • Sneezing: Transient sneezing episodes after application.
  • Headache: Mild headache associated with decongestant effect.
  • Local itching: Itching or mild irritation of the nasal lining.

Serious or Rare Side Effects

  • Rebound congestion: Worsening nasal blockage after prolonged use.
  • Severe allergic reaction: Rash, swelling, or difficulty breathing.
  • Nasal ulceration: Development of ulcerated lesions in the nasal cavity.
  • Hypertensive crisis: Marked increase in blood pressure in susceptible individuals.
  • Vision changes: Blurred vision or ocular discomfort if spray contacts the eyes.

Precautions & Warnings

When using Olynth Combo, consider the following safety measures:

  • Limit use: Do not exceed 3 days of continuous use to avoid rebound congestion.
  • Pre‑existing conditions: Use with caution if you have hypertension, heart disease or thyroid thyroid 
  • Pregnancy :
  • Use 

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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