Product image of Omacor (Omega-3-Acid Ethyl Esters 90) supplied by GNH India

Omacor

Active Ingredient:
Omega-3-Acid Ethyl Esters 90
Origin:
EU

Omacor (Omega-3-Acid Ethyl Esters 90)

Omega-3-acid ethyl esters, the active ingredient in Omacor, is a omega-3 fatty acid presented as a capsule for oral use. It treats hypertriglyceridemia in adult patients.
GNH India supplies Omacor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

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Basf As

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Indications & Clinical Uses

  • Omacor, an omega‑3 fatty acid medication, is used to manage disorders of lipid metabolism.
  • Hypertriglyceridemia: reduces elevated triglyceride concentrations and helps achieve target lipid levels.

How It Works

  • Omega-3-acid ethyl esters are metabolized to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These fatty acids inhibit hepatic diacylglycerol acyltransferase, decrease VLDL‑triglyceride synthesis, and enhance peripheral clearance of triglyceride‑rich lipoproteins, resulting in lower plasma triglyceride concentrations.

Side Effects

Common Side Effects

  • Fish‑like aftertaste: a transient metallic or marine taste.
  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Diarrhea: loose stools occurring shortly after dosing.
  • Headache: mild to moderate intensity.
  • Increased belching: occasional gas‑related symptoms.
  • Mild rash: occasional skin irritation.

Serious or Rare Side Effects

  • Pancreatitis: severe abdominal pain with elevated enzymes.
  • Bleeding tendency: prolonged bruising or hemorrhage, especially with anticoagulants.
  • Allergic reactions: urticaria, angioedema, or anaphylaxis.
  • Elevated liver enzymes: transaminase increases indicating hepatic stress.
  • Atrial fibrillation: irregular heartbeat reported in rare cases.
  • Severe hypotension: marked blood pressure drop when combined with antihypertensives.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Triglyceride monitoring: check baseline and periodic levels to assess efficacy.
  • Liver function: evaluate hepatic enzymes prior to treatment and during therapy.
  • Fish oil allergy: avoid if the patient has known hypersensitivity to marine oils.
  • Anticoagulant use: monitor coagulation parameters as bleeding risk may increase.
  • Pregnancy and breastfeeding: discuss potential risks with a healthcare professional.
  • Store at ambient temperature: keep capsules in the original container, protect from moisture and excessive heat.

Avoid Interactions

Omacor may interact with several drug classes. Review the following:

Major Interactions (Avoid)

  • Warfarin or other anticoagulants: increased bleeding risk.
  • High‑dose aspirin: additive antiplatelet effect.
  • Other omega‑3 supplements: excess EPA/DHA may amplify adverse effects.
  • Statins: potential for myopathy when combined with high doses.
  • Cyclosporine: may raise omega‑3 plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible additive blood‑pressure lowering.
  • Oral hypoglycemics: may affect glucose control.
  • Diuretics: monitor electrolytes if combined.
  • Immunosuppressants: observe for altered drug levels.
  • Vitamin E supplements: risk of excessive anticoagulation.

Frequently Asked Questions

Omacor is prescribed to lower high triglyceride levels in adults with hypertriglyceridemia. By reducing circulating triglycerides, it helps lower the risk of pancreatitis and supports overall lipid management as part of a broader therapeutic plan.

The ethyl esters are converted in the body to EPA and DHA, which inhibit hepatic triglyceride synthesis, reduce VLDL secretion, and increase peripheral clearance of triglyceride‑rich particles. This dual action lowers plasma triglyceride concentrations.

The exact dose of Omacor is determined by the prescribing clinician based on the patient’s triglyceride levels, response to therapy, and overall clinical condition. Dosage adjustments are made according to therapeutic goals and laboratory monitoring.

Safety data for Omacor in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting therapy.

To request Omacor, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Omacor contains purified omega‑3‑acid ethyl esters (EPA/DHA) at a high concentration, whereas many over‑the‑counter fish‑oil supplements contain lower doses and variable purity. Prescription‑grade Omacor provides more consistent triglyceride‑lowering efficacy and is subject to stricter regulatory standards.

Store Omacor capsules at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Omacor is taken orally as a capsule, usually with a meal to improve absorption. The capsule should be swallowed whole with water; it should not be opened, crushed, or chewed.

Serious risks include pancreatitis, significant bleeding especially when combined with anticoagulants, severe allergic reactions such as anaphylaxis, and rare elevations in liver enzymes. Patients should seek immediate medical attention if they experience severe abdominal pain, unusual bruising, or signs of an allergic response.

Individuals with a known allergy to fish oil or any component of the capsule should avoid Omacor. Patients with active bleeding disorders, uncontrolled liver disease, or those taking high‑dose anticoagulants without close monitoring should discuss alternatives with their physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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