Product image of Omedar (Omeprazole) supplied by GNH India

Omedar

Active Ingredient:
Omeprazole
Origin:
EU

Omedar (Omeprazole)

Omeprazole, the active ingredient in Omedar, is a proton pump inhibitor presented as a 20 mg tablet for oral use. It reduces stomach acid production and is used to treat conditions such as gastro‑oesophageal reflux disease and peptic ulcer disease in adults. GNH India supplies Omedar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Omedar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dar Al Dawa Pharma Srl

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Indications & Clinical Uses

Omeprazole acts on the gastric acid secretion pathway and is indicated for several acid‑related gastrointestinal conditions.

  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief and promotes healing of erosive esophagitis.
  • Peptic ulcer disease: supports ulcer healing and reduces risk of recurrence.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production.
  • Helicobacter pylori eradication regimens (as adjunct): enhances eradication success when combined with antibiotics.
  • NSA‑induced gastropathy prophylaxis: lowers risk of ulcer formation in high‑risk patients.

How It Works

  • Omeprazole selectively and irreversibly inhibits the H+/K+‑ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid secretion, it markedly reduces both basal and stimulated gastric acidity, allowing mucosal healing and symptom control in acid‑related disorders.

Side Effects

Adverse reactions to omeprazole are generally mild to moderate, but serious events can occur.

Common Side Effects

  • Headache: mild, transient headache.
  • Diarrhoea: loose stools, often self‑limiting.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: mild discomfort in the stomach region.
  • Flatulence: increased intestinal gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis presenting with watery diarrhoea.
  • Hypomagnesemia: low serum magnesium causing muscle cramps or cardiac arrhythmia.
  • Acute interstitial nephritis: kidney inflammation with reduced urine output.
  • Stevens‑Johnson syndrome/toxic epidermal necrolysis: severe skin reactions.
  • Fracture risk: increased incidence of hip, wrist or spine fractures with long‑term use.
  • Vitamin B12 deficiency: reduced absorption leading to anemia.

Precautions & Warnings

When prescribing Omedar, clinicians should consider several safety aspects.

  • Assess renal and hepatic function: adjust use if impairment is present.
  • Review concomitant medications: evaluate for potential drug‑drug interactions.
  • Monitor long‑term users: watch for magnesium deficiency, bone health and vitamin B12 levels.
  • Counsel pregnant or breastfeeding patients: use only if clearly needed.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and keep in original packaging.

Avoid Interactions

Omeprazole may interact with several medicines, altering their absorption or metabolism.

Major Interactions (Avoid)

  • Antifungal azoles (ketoconazole, itraconazole): reduced absorption leading to therapeutic failure.
  • HIV protease inhibitors (ritonavir, atazanavir): decreased plasma concentrations.
  • Clopidogrel: diminished antiplatelet effect, increasing cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in INR, requiring more frequent monitoring.
  • Phenytoin: reduced serum levels, possibly decreasing seizure control.
  • Digoxin: increased concentrations, raising risk of toxicity.

Frequently Asked Questions

Omedar contains omeprazole, a proton pump inhibitor that is used to lower stomach acid. It is commonly prescribed for conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, Zollinger‑Ellison syndrome, and as part of Helicobacter pylori eradication regimens.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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