Product image of Omeprazol Evolan (Omeprazole) supplied by GNH India

Omeprazol Evolan

Active Ingredient:
Omeprazole
Origin:
EU

Omeprazol Evolan (Omeprazole)

Omeprazole, the active ingredient in Omeprazol Evolan, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is employed in the management of gastro‑esophageal reflux disease, peptic ulcer disease, and related acid‑related conditions in adult patients.\n\nGNH India supplies Omeprazol Evolan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, transplant centres and oncology clinics worldwide, ensuring quality and regulatory compliance across markets.

Manufacturer / TM Owner

Evolan Pharma Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Omeprazole is a proton pump inhibitor used to manage conditions associated with excess gastric acid secretion.\n\nGastro‑esophageal reflux disease (GERD): reduces acid reflux symptoms and promotes healing of esophageal irritation.\nPeptic ulcer disease: facilitates ulcer healing by suppressing gastric acid production.\nNSAID‑induced ulcer prophylaxis: prevents ulcer formation in patients receiving non‑steroidal anti‑inflammatory drugs.\nHelicobacter pylori eradication (in combination therapy): enhances the effectiveness of antibiotic regimens by creating a less acidic gastric environment.\nAcid‑related dyspepsia: alleviates indigestion symptoms caused by excess gastric acid.

How It Works

  • Omeprazole irreversibly binds to the cysteine residues of the gastric H+/K+ ATPase enzyme (the proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to increased gastric pH and allowing mucosal healing. The inhibition is sustained for up to 72 hours, requiring new enzyme synthesis for acid production to resume.

Side Effects

  • Omeprazole is generally well tolerated, but adverse reactions may occur.\n\nCommon Side Effects:\n- Headache: mild, transient headache reported in some patients.\n- Diarrhea: loose stools or increased frequency of bowel movements.\n- Nausea: occasional feeling of queasiness, usually mild.\n- Abdominal pain: mild discomfort in the stomach area.\n- Flatulence: increased gas production leading to bloating.\n\nSerious or Rare Side Effects:\n- Clostridioides difficile infection: rare but severe colitis associated with altered gut flora, may cause watery diarrhea.\n- Hypomagnesemia: low magnesium levels with prolonged use, can lead to muscle cramps, tremors, or cardiac arrhythmias.\n- Acute interstitial nephritis: rare kidney inflammation presenting with reduced urine output, swelling, or elevated creatinine.\n- Fracture risk: long‑term therapy may be associated with increased incidence of bone fractures, especially in the hip, wrist, or spine.

Precautions & Warnings

  • When prescribing omeprazole, clinicians should consider several precautionary measures to ensure safe use.\n\nAssess renal function: evaluate kidney status and adjust therapy in severe impairment.\nMonitor magnesium: check serum magnesium levels during prolonged treatment to avoid deficiency.\nAvoid abrupt discontinuation: sudden stop may cause rebound acid hypersecretion and symptom recurrence.\nUse with caution in hepatic disease: limited data for patients with severe liver dysfunction.\nPregnancy and lactation: evaluate risk‑benefit before prescribing to pregnant or breastfeeding women.\nStore at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

  • Omeprazole may alter the pharmacokinetics of several medicines, leading to clinically relevant interactions.\n\nMajor Interactions (Avoid):\n- Clopidogrel: omeprazole reduces its antiplatelet activation, potentially decreasing efficacy.\n- Atazanavir: decreased absorption of this protease inhibitor when co‑administered, compromising HIV treatment.\n- Ketoconazole: reduced absorption when taken with omeprazole, may diminish antifungal effect.\n\nModerate Interactions (Monitor Closely):\n- Warfarin: omeprazole may increase INR; monitor coagulation parameters regularly.\n- Digoxin: higher serum levels reported; check cardiac function and drug levels as needed.\n- Methotrexate: high-dose therapy may raise methotrexate concentrations; monitor renal function and drug levels.\n- Phenytoin: omeprazole may increase phenytoin levels; monitor for toxicity.\n- Ciclosporin: omeprazole can raise ciclosporin concentrations; monitor renal function and drug levels.

Frequently Asked Questions

Omeprazol Evolan contains the active ingredient omeprazole, a proton pump inhibitor indicated for the treatment of gastro‑esophageal reflux disease (GERD), peptic ulcer disease, prevention of NSAID‑induced ulcers, and as part of combination therapy for Helicobacter pylori eradication. It works by reducing gastric acid secretion, helping to relieve symptoms and promote healing of acid‑related lesions.

Omeprazole acts by irreversibly binding to the H+/K+ ATPase enzyme, commonly called the gastric proton pump, located on the secretory surface of parietal cells. This binding blocks the final step of acid production, leading to a sustained increase in gastric pH and allowing the gastrointestinal mucosa to heal from acid‑induced damage.

The appropriate dose of Omeprazol Evolan is determined by the prescribing healthcare professional based on the specific indication, severity of disease, patient age, renal function, and any concomitant medications. Dosage regimens may differ for short‑term ulcer healing versus long‑term maintenance, and the prescriber will tailor the regimen to each individual patient.

Safety data for omeprazole in pregnancy and lactation are limited. The drug is classified as a Category C medication in many regions, meaning risk cannot be ruled out. Clinicians should weigh the potential benefits against possible risks and consider alternative therapies when treating pregnant or nursing women.

To order Omeprazol Evolan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India serves hospitals, pharmacies,

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Omeprazole

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT