Product image of Omeprazol Generis (Omeprazole) supplied by GNH India

Omeprazol Generis

Active Ingredient:
Omeprazole
Origin:
EU

Omeprazol Generis (Omeprazole)

Omeprazole, the active ingredient in Omeprazol Generis, is a proton pump inhibitor presented as a tablet for oral use. It reduces gastric acid production and is used to treat acid‑related disorders such as gastro‑esophageal reflux disease and peptic ulcer disease in adults, indicated for short‑term and maintenance therapy and is available in standard strengths for convenient dosing.

GNH India supplies Omeprazol Generis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution across EU and other regulated markets.

Manufacturer / TM Owner

Generis Farmacêutica, S.A.

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Indications & Clinical Uses

Omeprazole is a proton pump inhibitor used to reduce gastric acid secretion in several acid‑related conditions.

  • Gastro‑esophageal reflux disease (GERD): alleviates heartburn and esophageal irritation.
  • Peptic ulcer disease: promotes ulcer healing and prevents recurrence.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion.
  • Erosive esophagitis: heals mucosal damage caused by acid exposure.
  • NSAID‑induced ulcer prophylaxis: reduces risk of ulcer formation in patients on chronic NSAIDs.

How It Works

  • Omeprazole irreversibly binds to the H+/K+‑ATPase enzyme (the gastric proton pump) on the secretory surface of parietal cells, inhibiting the final step of acid production. This suppression of gastric acid secretion raises gastric pH, allowing ulcer healing and relief of acid‑related symptoms.

Side Effects

Common Side Effects

  • Headache: mild to moderate pain.
  • Abdominal pain: discomfort in the stomach area.
  • Diarrhea: loose stools.
  • Nausea: feeling of sickness.
  • Flatulence: excess gas.
  • Constipation: difficulty passing stools.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis.
  • Severe allergic reactions: rash, swelling, anaphylaxis.
  • Stevens‑Johnson syndrome: skin blistering.
  • Elevated liver enzymes: potential hepatic injury.
  • Hypomagnesemia: low magnesium levels.
  • Increased risk of bone fractures: with long‑term use.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess renal and hepatic function: adjust use if impairment is present.
  • Use caution in elderly patients: higher incidence of adverse effects.
  • Avoid concomitant use with drugs that require acidic environment for absorption.
  • Monitor magnesium levels during prolonged treatment.
  • Consider dose adjustment in severe hepatic impairment.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Omeprazole may interact with several medications; review the following:

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect.
  • Atazanavir: decreased antiviral absorption.
  • HIV protease inhibitors (e.g., ritonavir): altered plasma concentrations.
  • Methotrexate: increased toxicity risk.

Moderate Interactions (Monitor Closely)

  • Digoxin: increased serum levels.
  • Phenytoin: reduced efficacy.
  • Phenobarbital: decreased omeprazole exposure.
  • Ketoconazole: reduced antifungal absorption.

Frequently Asked Questions

Omeprazol Generis contains omeprazole, a proton pump inhibitor indicated for gastro‑esophageal reflux disease, peptic ulcer disease, Zollinger‑Ellison syndrome, erosive esophagitis, and for preventing NSAID‑induced ulcers.

Omeprazole irreversibly inhibits the gastric H+/K+‑ATPase (proton pump) on parietal cells, blocking the final step of acid secretion and thereby raising gastric pH, which promotes healing of acid‑related lesions.

The prescribed dose of Omeprazol Generis is determined by the treating physician based on the specific indication, patient characteristics, and clinical response. Dosage regimens are not standardized and should follow the prescriber’s instructions.

Omeprazole is classified as pregnancy category C; it should only be used if the potential benefit justifies the potential risk to the fetus. Limited data are available for breastfeeding, and a healthcare professional should evaluate the risk‑benefit balance.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Omeprazol Generis, as a proton pump inhibitor, provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy is similar, but individual patient response and drug‑interaction profiles may differ.

Store Omeprazol Generis tablets at room temperature, below 25 °C, in the original packaging, and protect them from moisture and direct sunlight to maintain stability.

Omeprazol Generis tablets are taken orally, usually before a meal, with a glass of water. The exact timing and frequency should follow the prescribing clinician’s directions.

Serious risks include Clostridioides difficile infection, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, liver enzyme elevations, low magnesium levels, and increased fracture risk with long‑term use.

Patients with known hypersensitivity to omeprazole or any component of the formulation should avoid it. Caution is also advised for individuals with severe liver disease, and it should be used under medical supervision in pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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