Product image of Omeprazol Hennig (Omeprazole) supplied by GNH India

Omeprazol Hennig

Active Ingredient:
Omeprazole
Origin:
EU

Omeprazol Hennig (Omeprazole)

Omeprazole, the active ingredient in Omeprazol Hennig, is a proton pump inhibitor presented as a 20 mg tablet for oral use. It reduces stomach acid production and is used to treat acid‑related gastrointestinal conditions in adults and children.

GNH India supplies Omeprazol Hennig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hennig Arzneimittel Gmbh & Co. Kg

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Indications & Clinical Uses

Omeprazol Hennig is a proton pump inhibitor that acts on the gastric acid secretion pathway. It is indicated for several acid‑related disorders:

  • Gastro‑oesophageal reflux disease (GERD): provides relief of heartburn and promotes healing of erosive esophagitis.
  • Peptic ulcer disease: supports ulcer healing and reduces risk of recurrence.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid secretion associated with the condition.

How It Works

  • Omeprazole selectively and irreversibly inhibits the H+/K+‑ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid production, it markedly lowers gastric acidity, allowing mucosal healing and symptom relief.

Side Effects

Adverse reactions to Omeprazole may vary in frequency and severity.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: usually self‑limiting.
  • Nausea: occasional and transient.
  • Abdominal pain: mild discomfort.
  • Flatulence: increased intestinal gas.
  • Constipation: occasional bowel habit change.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: persistent watery diarrhoea.
  • Low magnesium levels (hypomagnesemia): muscle cramps, irregular heartbeat.
  • Bone fractures: increased risk with long‑term use.
  • Liver enzyme elevation: signs of hepatic stress.
  • Acute interstitial nephritis: kidney inflammation.

Precautions & Warnings

When prescribing Omeprazol Hennig, consider the following safety measures:

  • Assess renal and hepatic function: adjust use if impairment.
  • Review concomitant medications: potential for altered drug levels.
  • Monitor long‑term users: watch for nutrient deficiencies and bone health.
  • Use with caution in pregnancy: weigh benefits against potential risks.
  • Avoid in patients with known hypersensitivity to omeprazole or other PPIs.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Omeprazole can affect the pharmacokinetics of several co‑administered drugs.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, increasing cardiovascular risk.
  • Atazanavir: decreased antiviral absorption, compromising HIV therapy.
  • Methotrexate (high dose): increased systemic exposure, risk of toxicity.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR, requiring more frequent monitoring.
  • Phenytoin: reduced serum concentrations, may diminish seizure control.
  • Digoxin: modest increase in levels, watch for signs of toxicity.

Frequently Asked Questions

Omeprazol Hennig contains omeprazole, a proton pump inhibitor that is prescribed for acid‑related gastrointestinal disorders such as gastro‑oesophageal reflux disease, peptic ulcer disease and Zollinger‑Ellison syndrome. It works by lowering stomach acid, which helps relieve symptoms and promotes healing of the gastrointestinal lining.

Omeprazole blocks the H+/K+‑ATPase enzyme, also known as the gastric proton pump, on the surface of stomach parietal cells. This inhibition stops the final step of acid secretion, leading to a sustained decrease in gastric acidity and allowing damaged tissue to heal.

The dosage of Omeprazol Hennig is determined by the prescribing clinician based on the specific indication, patient age, severity of disease and any relevant comorbidities. The prescriber will set the appropriate strength, frequency and duration of therapy.

Omeprazole is classified as pregnancy category B in many regions, indicating no evidence of risk in animal studies but limited human data. It should be used only if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult a healthcare professional, as small amounts may be excreted in milk.

To request Omeprazol Hennig, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.

Omeprazole belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, omeprazole has a well‑established efficacy and safety profile, though individual response and drug‑interaction potential may vary.

Store Omeprazol Hennig tablets at ambient temperature, below 25 °C, in the original packaging. Protect the product from moisture, humidity and direct sunlight to maintain potency throughout its shelf life.

Omeprazol Hennig is taken orally, usually as a whole tablet swallowed with water. It is commonly recommended to take the dose before a meal, often in the morning, but patients should follow the prescribing clinician’s instructions regarding timing and food intake.

Serious adverse reactions, though rare, include severe allergic responses (anaphylaxis), Clostridioides difficile‑associated colitis, low magnesium levels, bone fractures with long‑term use, and acute interstitial nephritis. Patients should seek immediate medical attention if they experience symptoms such as rash, persistent diarrhoea, muscle cramps or unexplained kidney problems.

Individuals with a known hypersensitivity to omeprazole, other proton pump inhibitors, or any excipients in the tablet should avoid the product. Caution is also advised for patients with severe liver disease, and it should be used only under medical supervision in those with significant renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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