Product image of Omeprazol Proclor (Omeprazole) supplied by GNH India

Omeprazol Proclor

Active Ingredient:
Omeprazole
Origin:
EU

Omeprazol Proclor (Omeprazole)

Omeprazole, the active ingredient in Omeprazol Proclor, is a proton pump inhibitor presented as a strength/form for oral use. It reduces stomach acid production and is used to treat conditions such as gastro‑oesophageal reflux disease and peptic ulcer disease in adults and children. GNH India supplies Omeprazol Proclor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Omeprazol Proclor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pentafarma - Sociedade Tecnico-Medicinal S.A.

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Indications & Clinical Uses

Omeprazole acts on the gastric acid secretion pathway and is indicated for several acid‑related disorders.

  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief and promotes healing of erosive esophagitis.
  • Peptic ulcer disease: supports ulcer healing and reduces recurrence risk.
  • Zollinger‑Ellison syndrome: controls gastric acid hypersecretion.
  • Erosive gastritis: aids mucosal healing and symptom control.
  • NSAID‑induced ulcer prophylaxis: lowers the risk of ulcer development in at‑risk patients.

How It Works

  • Omeprazole selectively and irreversibly inhibits the H+/K+‑ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid production, it markedly reduces both basal and stimulated gastric acidity, allowing the gastrointestinal mucosa to heal and symptoms to improve.

Side Effects

Adverse reactions to omeprazole vary in frequency and severity.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: typically self‑limiting.
  • Nausea: occasional and transient.
  • Abdominal pain: mild discomfort.
  • Flatulence: occasional gas buildup.
  • Constipation: infrequent bowel changes.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis risk.
  • Acute interstitial nephritis: renal inflammation.
  • Hypomagnesemia: low serum magnesium levels.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Hepatotoxicity: elevated liver enzymes.
  • Bone fracture risk: long‑term use associated with decreased bone density.

Precautions & Warnings

When using Omeprazol Proclor, certain precautions should be observed to ensure safe and effective therapy.

  • Assess renal function: dose adjustment may be needed in severe impairment.
  • Monitor magnesium levels: prolonged use can lead to hypomagnesemia.
  • Evaluate for H. pylori infection: eradication therapy may be required concurrently.
  • Use cautiously in pregnancy: weigh potential benefits against risks.
  • Avoid long‑term use without reassessment: consider step‑down therapy.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Omeprazole may interact with several medicines, altering their absorption or metabolism.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect.
  • Atorvastatin: increased plasma concentration.
  • Warfarin: potential increase in anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Digoxin: elevated serum levels.
  • Methotrexate: reduced renal clearance.
  • Phenytoin: altered plasma concentrations.
  • Ketoconazole: decreased absorption due to higher gastric pH.
  • Iron supplements: reduced absorption efficiency.

Frequently Asked Questions

Omeprazol Proclor contains omeprazole, a proton pump inhibitor used to lower stomach acid. It is prescribed for conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, Zollinger‑Ellison syndrome, erosive gastritis and for preventing NSA‑related ulcers in at‑risk patients.

Omeprazole blocks the H+/K+‑ATPase enzyme, also known as the gastric proton pump, on the surface of stomach parietal cells. This irreversible inhibition stops the final step of acid secretion, reducing both basal and stimulated gastric acidity and allowing the gastrointestinal lining to heal.

The specific dose and treatment duration are determined by the prescribing clinician based on the patient’s condition, age, and response to therapy. Healthcare professionals tailor the regimen to achieve optimal acid control while minimizing risks.

Omeprazole is classified as pregnancy category B in many regions, indicating no proven risk in animal studies but limited human data. It should be used only if clearly needed, and the benefits outweigh potential risks. Limited data suggest it is excreted in breast milk in small amounts; breastfeeding mothers should consult their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Omeprazole belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with newer PPIs, omeprazole has a well‑established efficacy and safety profile, though individual response and drug‑interaction potential may vary.

Store Omeprazol Proclor at ambient temperature, below 25 °C, in its original container. Protect the product from moisture, direct sunlight and excessive heat to maintain its stability and potency.

Omeprazol Proclor is taken orally, usually as a tablet or capsule, with water. It is commonly recommended to swallow the dose before a meal, often in the morning, but exact instructions should follow the prescribing clinician’s guidance.

Serious adverse events, though rare, include Clostridioides difficile‑associated colitis, acute interstitial nephritis, severe hypersensitivity reactions such as Stevens‑Johnson syndrome, and low magnesium levels that can lead to cardiac arrhythmias. Patients should seek medical attention if they experience severe abdominal pain, persistent diarrhea, rash or muscle weakness.

Individuals with known hypersensitivity to omeprazole or any component of the formulation should avoid it. Caution is also advised for patients with severe liver disease, those taking interacting medications such as clopidogrel without medical supervision, and pregnant or breastfeeding women unless the benefit justifies potential risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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