Product image of Omeprazol Xiromed (Omeprazole) supplied by GNH India

Omeprazol Xiromed

Active Ingredient:
Omeprazole
Origin:
EU

Omeprazol Xiromed (Omeprazole)

Omeprazole, the active ingredient in Omeprazol Xiromed, is a proton pump inhibitor presented as a 20 mg tablet for oral use. It reduces stomach acid production and is used to treat acid‑related disorders in adults and children.
GNH India supplies Omeprazol Xiromed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medical Valley Invest Ab

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Indications & Clinical Uses

Omeprazol Xiromed is a proton pump inhibitor that acts on gastric acid secretion pathways.

  • Gastro‑esophageal reflux disease (GERD): provides symptomatic relief and promotes healing of esophageal erosion.
  • Peptic ulcer disease: supports ulcer healing and reduces risk of recurrence.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production associated with the condition.

How It Works

  • Omeprazole selectively and irreversibly binds to the H+/K+‑ATPase enzyme (the gastric proton pump) on the parietal cell surface, inhibiting its activity. This blockade prevents the final step of acid secretion, leading to a sustained increase in gastric pH and reduction of gastric acidity.

Side Effects

Adverse reactions to Omeprazol Xiromed vary in frequency and severity.

Common Side Effects

  • Headache: mild and transient.
  • Diarrhea: usually self‑limiting.
  • Nausea: occasional mild discomfort.
  • Abdominal pain: mild cramping.
  • Flatulence: increased intestinal gas.
  • Constipation: occasional bowel habit change.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis risk.
  • Acute interstitial nephritis: kidney inflammation.
  • Stevens‑Johnson syndrome: severe skin reaction.
  • Hypersensitivity reactions: rash, angioedema, anaphylaxis.
  • Fracture risk: decreased bone mineral density with long‑term use.

Precautions & Warnings

When using Omeprazol Xiromed, consider the following safety measures:

  • Assess renal function: adjust use in severe renal impairment.
  • Review hepatic status: use cautiously in moderate liver disease.
  • Monitor long‑term therapy: evaluate need for continued treatment after 12 months.
  • Avoid unnecessary concomitant NSAID use: increased ulcer risk.
  • Counsel on symptom monitoring: report persistent abdominal pain or vomiting.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Omeprazole can affect the plasma levels of several co‑administered medicines.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, increasing cardiovascular event risk.
  • Atazanavir: markedly decreased absorption, compromising HIV therapy.
  • Methotrexate (high dose): increased systemic exposure, risk of toxicity.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential INR elevation, requiring closer monitoring.
  • Phenytoin: possible reduction in serum levels, may need dose adjustment.
  • Digoxin: modest increase in concentration, monitor for toxicity.

Frequently Asked Questions

Omeprazol Xiromed contains omeprazole, a proton pump inhibitor that is prescribed for acid‑related conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease and Zollinger‑Ellison syndrome. It works by lowering stomach acidity, which helps relieve symptoms and promotes healing of the gastrointestinal lining.

Omeprazole blocks the H+/K+‑ATPase enzyme, also known as the gastric proton pump, on the surface of stomach parietal cells. By irreversibly inhibiting this pump, it stops the final step of acid secretion, leading to a sustained rise in gastric pH and reduced acidity.

The prescribed dose of Omeprazol Xiromed is determined by a qualified healthcare professional based on the specific indication, patient age, weight and clinical response. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Omeprazole is classified as pregnancy category B in the EU, indicating no evidence of risk in animal studies and a lack of well‑controlled human data. It may be used during pregnancy or lactation only if the potential benefit justifies the potential risk, and under medical supervision.

To place an order, submit an enquiry on the Omeprazol Xiromed product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Omeprazole belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, omeprazole has a well‑established efficacy and safety profile, though individual response and drug‑interaction potential may vary.

Store Omeprazol Xiromed tablets below 25 °C in their original container, protected from moisture, heat and direct sunlight. Do not use the product after the expiry date printed on the packaging.

Omeprazol Xiromed is taken orally, usually as a whole tablet with water. It is commonly recommended to swallow the tablet before a meal, often in the morning, but patients should follow the specific timing advised by their prescriber.

Serious adverse events, although rare, can include Clostridioides difficile‑associated colitis, acute interstitial nephritis, severe skin reactions such as Stevens‑Johnson syndrome, and hypersensitivity reactions that may lead to anaphylaxis. Patients should seek immediate medical attention if they experience severe rash, fever, persistent diarrhea or unexplained kidney problems.

Omeprazol Xiromed is contraindicated in individuals with known hypersensitivity to omeprazole or any other component of the formulation. Caution is also advised for patients with severe liver disease, those taking certain interacting medications such as clopidogrel, and patients who have experienced previous severe adverse reactions to proton pump inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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