Product image of Omeprazol Zintem (Omeprazole) supplied by GNH India

Omeprazol Zintem

Active Ingredient:
Omeprazole
Origin:
EU

Omeprazol Zintem (Omeprazole)

Omeprazole, the active ingredient in Omeprazol Zintem, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease and for ulcer prophylaxis in patients taking NSAIDs.

GNH India supplies Omeprazol Zintem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance through a robust distribution network.

Manufacturer / TM Owner

Towa Pharmaceutical S.A.

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Indications & Clinical Uses

Omeprazol Zintem is a proton pump inhibitor that acts on the gastric acid secretion pathway, providing relief in several acid‑related disorders.

  • Gastro‑oesophageal reflux disease (GERD): reduces acid exposure, relieving heartburn and regurgitation.
  • Erosive esophagitis: promotes healing of inflamed esophageal tissue.
  • Peptic ulcer disease: facilitates ulcer healing and symptom control.
  • NSAID‑induced ulcer prophylaxis: lowers risk of ulcer formation in patients on non‑steroidal anti‑inflammatory drugs.
  • Helicobacter pylori eradication (in combination therapy): enhances effectiveness of antibiotic regimens.

How It Works

  • Omeprazole irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid secretion, it markedly reduces the production of gastric acid, leading to increased gastric pH and allowing healing of acid‑related mucosal damage.

Side Effects

Adverse reactions may occur with Omeprazol Zintem. The following side effects have been reported.

Common Side Effects

  • Headache: mild to moderate intensity, often transient.
  • Abdominal pain: discomfort in the upper abdomen.
  • Diarrhoea: loose stools that may be watery.
  • Nausea: feeling of queasiness.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: severe diarrhoea with abdominal cramping.
  • Low magnesium levels (hypomagnesemia): muscle cramps, irregular heartbeat.

Precautions & Warnings

When using Omeprazol Zintem, consider the following precautions.

  • Assess renal function: dose may need adjustment in severe renal impairment.
  • Monitor magnesium levels: prolonged therapy can cause hypomagnesemia.
  • Avoid abrupt discontinuation: may lead to rebound acid hypersecretion.
  • Use with caution in liver disease: monitor hepatic function tests.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Omeprazol Zintem can interact with several medicines. Review the following categories.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, increasing cardiovascular risk.
  • Atazanavir: decreased absorption, lowering antiviral efficacy.
  • High‑dose methotrexate: increased toxicity due to reduced clearance.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, requiring closer coagulation monitoring.
  • Digoxin: may raise serum digoxin levels, necessitating dosage adjustment.

Frequently Asked Questions

Omeprazol Zintem contains omeprazole, a proton pump inhibitor indicated for the treatment of gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease, prevention of NSAID‑induced ulcers, and as part of combination therapy for Helicobacter pylori eradication.

Omeprazole blocks the H+/K+ ATPase enzyme, also known as the gastric proton pump, in the parietal cells of the stomach. By irreversibly inhibiting this pump, it suppresses the final step of acid secretion, leading to a sustained increase in gastric pH and allowing acid‑related lesions to heal.

The appropriate dose of Omeprazol Zintem is determined by the prescribing healthcare professional based on the specific indication, patient age, renal function and other clinical factors. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.

Safety data for omeprazole in pregnancy and lactation are limited. The prescriber will weigh potential benefits against possible risks before recommending use. Women who are pregnant, planning pregnancy, or breastfeeding should discuss any concerns with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Omeprazol Zintem belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, omeprazole has a well‑established efficacy and safety profile, though individual response may vary.

Omeprazol Zintem should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or direct sunlight.

Omeprazol Zintem is taken orally, usually as a tablet or capsule, with a glass of water. It is generally recommended to swallow the dose whole, preferably before a meal, unless the prescriber provides alternative instructions.

Serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated diarrhoea, and low magnesium levels that can cause muscle cramps or cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms like rash, swelling, persistent diarrhoea, or irregular heartbeat.

Individuals with known hypersensitivity to omeprazole or any component of the formulation should avoid using Omeprazol Zintem. Caution is also advised for patients with severe liver disease, certain bone disorders, or those taking medications that have major interactions with omeprazole.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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