Product image of Omeprazole Sandoz (Omeprazole) supplied by GNH India

Omeprazole Sandoz

Active Ingredient:
Omeprazole
Origin:
EU

Omeprazole Sandoz (Omeprazole)

Omeprazole, the active ingredient in Omeprazole Sandoz, is a proton pump inhibitor presented as an intravenous formulation for hospital use. It reduces gastric acid secretion and is used to treat conditions such as gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease, and to prevent NSAID‑induced ulcers.

GNH India supplies Omeprazole Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Sandoz Polska Sp. Z O.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Omeprazole Sandoz is a proton pump inhibitor used to manage acid‑related gastrointestinal disorders.

  • Gastro‑oesophageal reflux disease (GERD): provides symptomatic relief by decreasing gastric acid exposure to the esophagus.
  • Erosive esophagitis: promotes healing of acid‑induced esophageal lesions.
  • Peptic ulcer disease: supports ulcer healing and reduces recurrence risk.
  • Prevention of NSAID‑induced ulcers: protects the gastric mucosa in patients receiving non‑steroidal anti‑inflammatory drugs.

How It Works

  • Omeprazole Sandoz irreversibly binds to the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, leading to an increased gastric pH and allowing mucosal healing in acid‑related conditions.

Side Effects

Adverse reactions may occur with any medication, and patients should be monitored for both common and serious events.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: usually transient.
  • Nausea: may occur after infusion.
  • Abdominal pain: mild discomfort in the upper abdomen.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis requiring medical attention.
  • Severe allergic reaction (anaphylaxis): rapid onset of rash, swelling, and respiratory difficulty.
  • Hypomagnesemia: low serum magnesium with prolonged use.
  • Liver enzyme elevation: increased ALT/AST levels.
  • Stevens‑Johnson syndrome: rare but life‑threatening skin reaction.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Assess renal function: adjust therapy in patients with severe renal impairment.
  • Monitor magnesium levels: prolonged treatment may lead to hypomagnesemia.
  • Use cautiously in hepatic disease: omeprazole is metabolised by the liver.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Omeprazole Sandoz can affect the pharmacokinetics of several co‑administered drugs.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, increasing cardiovascular risk.
  • Atazanavir: decreased absorption, compromising antiviral efficacy.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, requiring closer coagulation monitoring.
  • Methotrexate: elevated serum levels, especially at high doses.
  • Digoxin: may increase serum digoxin concentrations, necessitating dose adjustment.

Frequently Asked Questions

Omeprazole Sandoz is indicated for the treatment of gastro‑oesophageal reflux disease, erosive esophagitis, peptic ulcer disease, and for the prevention of ulcers associated with long‑term non‑steroidal anti‑inflammatory drug therapy. It works by reducing gastric acid secretion, which helps relieve symptoms and promotes healing of the gastrointestinal lining.

Omeprazole inhibits the H+/K+ ATPase pump, also known as the gastric proton pump, located on the secretory surface of parietal cells. By irreversibly blocking this enzyme, it prevents the final step of acid production, leading to a sustained increase in gastric pH and reduced acid exposure to the esophagus and stomach lining.

The specific dose and infusion rate of Omeprazole Sandoz are determined by the prescribing clinician based on the patient’s condition, severity, and clinical response. Healthcare professionals should follow local prescribing guidelines and adjust the regimen as needed for individual patients.

The safety of Omeprazole Sandoz in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider after careful consideration.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements), and assists with import documentation.

Omeprazole Sandoz belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its intravenous formulation allows rapid onset of action, making it suitable for inpatient settings where oral administration is not feasible.

Omeprazole Sandoz should be stored at ambient temperature, below 25 °C, in its original packaging. The container should be kept away from moisture and direct sunlight to maintain product stability. Do not freeze the solution.

Omeprazole Sandoz is given by intravenous infusion under the supervision of qualified healthcare personnel. The infusion rate and duration are determined by the prescribing clinician, and the medication should be administered using aseptic technique in a clinical setting.

Serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, significant hypomagnesemia with prolonged use, and rare skin reactions like Stevens‑Johnson syndrome. Patients should be monitored for any signs of these conditions, and treatment should be discontinued if they occur.

Omeprazole Sandoz is contraindicated in patients with known hypersensitivity to omeprazole, other proton pump inhibitors, or any of the formulation excipients. It should also be avoided in individuals with a history of severe allergic reactions to similar medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.