Product image of Omeprazole Stada (Omeprazole) supplied by GNH India

Omeprazole Stada

Active Ingredient:
Omeprazole
Origin:
EU

Omeprazole Stada (Omeprazole)

Omeprazole, the active ingredient in Omeprazole Stada, is a proton‑pump inhibitor presented as a tablet for oral use. It reduces stomach acid production and is used to treat conditions such as gastro‑oesophageal reflux disease and peptic ulcer disease in adults.
GNH India supplies Omeprazole Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Omeprazole Stada is a proton‑pump inhibitor that acts on the gastric acid secretion pathway. It is indicated for several acid‑related gastrointestinal conditions:

  • Gastro‑esophageal reflux disease (GERD): alleviates heartburn and promotes healing of the esophageal lining.
  • Peptic ulcer disease: supports ulcer healing and reduces recurrence risk.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production associated with gastrin‑secreting tumors.
  • Erosive esophagitis: facilitates mucosal healing in acid‑induced esophageal injury.
  • Helicobacter pylori eradication regimens: used as part of combination therapy to improve eradication rates.

How It Works

  • Omeprazole selectively and irreversibly inhibits the H+/K+‑ATPase enzyme (the gastric proton pump) located in the parietal cells of the stomach lining. By blocking this final step of acid secretion, it markedly lowers gastric acidity, allowing damaged mucosa to heal and reducing symptoms associated with hyperacidity.

Side Effects

Omeprazole Stada is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: usually transient.
  • Nausea: occasional mild upset.
  • Abdominal pain: mild cramping.
  • Flatulence: increased gas.
  • Constipation: occasional bowel habit change.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis risk.
  • Acute interstitial nephritis: kidney inflammation.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Low magnesium levels: may cause muscle cramps or arrhythmia.
  • Fracture risk: long‑term use linked to reduced bone density.

Precautions & Warnings

When prescribing Omeprazole Stada, consider the following safety measures:

  • Assess renal function: adjust use in severe impairment.
  • Review liver status: use with caution in hepatic disease.
  • Evaluate need for long‑term therapy: monitor bone health.
  • Monitor for infections: be alert to signs of C. difficile.
  • Pregnancy and lactation: weigh benefits against potential risks.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Omeprazole Stada can affect the pharmacokinetics of several co‑administered medicines.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, may increase cardiovascular risk.
  • Atazanavir: decreased antiviral absorption, may lead to treatment failure.
  • Ketoconazole: markedly reduced antifungal exposure.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in INR, monitor coagulation.
  • Phenytoin: decreased serum levels, watch for seizure control.
  • Digoxin: modest rise in concentration, assess for toxicity.

Frequently Asked Questions

Omeprazole Stada is indicated for acid‑related gastrointestinal disorders such as gastro‑oesophageal reflux disease, peptic ulcer disease, Zollinger‑Ellison syndrome, erosive esophagitis and as part of Helicobacter pylori eradication regimens. It helps lower stomach acidity, relieving symptoms and promoting mucosal healing.

Omeprazole blocks the H+/K+‑ATPase enzyme, also known as the gastric proton pump, in the stomach’s parietal cells. This irreversible inhibition stops the final step of acid secretion, leading to a sustained reduction in gastric acidity and allowing damaged tissue to recover.

The appropriate dose of Omeprazole Stada is determined by the prescribing healthcare professional based on the specific indication, severity of the condition, and patient factors. Dosage regimens are individualized and should follow the prescriber’s instructions.

Omeprazole is classified as pregnancy category B in many regions, indicating no proven risk in animal studies but limited human data. It may be used during pregnancy or lactation only if clearly needed and after a risk‑benefit assessment by the prescriber.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Omeprazole belongs to the proton‑pump inhibitor class, offering more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, it has a similar efficacy profile, with differences mainly in pharmacokinetic properties and individual patient response.

Store Omeprazole Stada at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Omeprazole Stada is taken orally, usually as a whole tablet swallowed with water. It is commonly recommended to take the dose before a meal, often in the morning, but patients should follow the specific instructions provided by their healthcare professional.

Serious risks, though uncommon, include Clostridioides difficile‑associated colitis, acute interstitial nephritis, severe allergic reactions such as anaphylaxis, and low magnesium levels that can cause cardiac arrhythmias. Patients should seek immediate medical attention if they experience any of these symptoms.

Omeprazole Stada is contraindicated in individuals with known hypersensitivity to omeprazole or any component of the formulation. Caution is also advised for patients with severe liver disease, those taking interacting medications like clopidogrel, and patients requiring long‑term acid suppression without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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