Product image of Omeprazolo Hikma (Omeprazole Sodium) supplied by GNH India

Omeprazolo Hikma

Active Ingredient:
Omeprazole Sodium
Origin:
EU

Omeprazolo Hikma (Omeprazole Sodium)

Omeprazole, the active ingredient in Omeprazolo Hikma, is a proton pump inhibitor presented as a tablet for oral use. It reduces stomach acid production and is used to treat conditions such as gastro‑oesophageal reflux disease and peptic ulcer disease in adults and adolescents. GNH India supplies Omeprazolo Hikma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Omeprazolo Hikma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hikma Farmacêutica (Portugal), S.A.

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Indications & Clinical Uses

Omeprazolo Hikma is a proton pump inhibitor that acts on the gastric acid secretion pathway.

  • Gastro‑esophageal reflux disease (GERD): provides symptomatic relief and promotes healing of erosive esophagitis.
  • Peptic ulcer disease: supports ulcer healing and reduces recurrence risk.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production.
  • Helicobacter pylori eradication regimens (as adjunct): enhances eradication success when combined with antibiotics.
  • NSAID‑associated ulcer prophylaxis: lowers risk of ulcer formation in high‑risk patients.

How It Works

  • Omeprazole sodium is a benzimidazole derivative that irreversibly binds to the H+/K+‑ATPase enzyme (the gastric proton pump) on the secretory surface of parietal cells. By inhibiting this final step of acid secretion, it markedly lowers gastric acidity, allowing mucosal healing and symptom control.

Side Effects

Omeprazolo Hikma may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Flatulence
  • Constipation

Serious or Rare Side Effects

  • Clostridioides difficile infection
  • Acute interstitial nephritis
  • Severe allergic reactions (anaphylaxis, angio‑edema)
  • Low magnesium levels (hypomagnesemia)
  • Fracture risk with long‑term use
  • Vitamin B12 deficiency with prolonged therapy

Precautions & Warnings

Before initiating Omeprazolo Hikma, consider the following safety points:

  • Assess renal function: dose adjustment may be needed in severe impairment.
  • Review concomitant medications: potential for altered absorption of drugs requiring acidic pH.
  • Monitor long‑term users: watch for bone density loss, magnesium and vitamin B12 levels.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation.
  • Elderly patients: start at the lowest effective dose and monitor for falls.
  • Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Omeprazolo Hikma can affect the plasma concentrations of several co‑administered medicines.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, consider alternative therapy.
  • Atazanavir/ritonavir: markedly decreased antiviral exposure, contraindicated.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, monitor coagulation parameters.
  • Digoxin: increased serum levels, check renal function and drug levels.
  • Methotrexate (high dose): reduced clearance, monitor for toxicity.
  • Iron supplements: decreased absorption, separate dosing by at least 2 h.

Frequently Asked Questions

Omeprazolo Hikma contains omeprazole sodium, a proton pump inhibitor that is used to lower stomach acid. It is indicated for conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, Zollinger‑Ellison syndrome and for ulcer prevention in patients taking non‑steroidal anti‑inflammatory drugs.

Omeprazole irreversibly inhibits the H+/K+‑ATPase (gastric proton pump) on the secretory surface of parietal cells. By blocking this final step of acid secretion, it reduces gastric acidity, allowing the oesophageal and gastric mucosa to heal and relieving acid‑related symptoms.

The prescribed dose of Omeprazolo Hikma is determined by the treating physician based on the specific indication, patient age, renal function and response to therapy. Dosage regimens are individualized and should follow local prescribing guidelines.

Omeprazole is classified as pregnancy category B in many regions, indicating no evidence of risk in animal studies but limited human data. It may be used during pregnancy or lactation only when clearly needed, after a risk‑benefit assessment by the healthcare professional.

To place an order, submit an enquiry on the Omeprazolo Hikma product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Omeprazole belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with newer PPIs, omeprazole has a well‑established efficacy and safety profile, though individual response and drug‑interaction potential may vary.

Omeprazolo Hikma tablets should be stored at temperatures not exceeding 25 °C. Keep the product in its original blister pack, protect it from moisture and direct sunlight, and discard any tablets that appear discoloured or damaged.

The tablets are taken orally, usually before a meal—most commonly before breakfast. Swallow the tablet whole with a glass of water; do not crush, chew or split unless specifically instructed by a healthcare professional.

Serious but uncommon risks include Clostridioides difficile‑associated colitis, acute interstitial nephritis, severe allergic reactions, hypomagnesemia and increased fracture risk with prolonged use. Patients should be monitored for these events, especially during long‑term therapy.

Omeprazolo Hikma is contraindicated in individuals with known hypersensitivity to omeprazole or any excipients in the tablet. Caution is also advised for patients with severe liver impairment, and it should be avoided in those taking medications that have a contraindicated interaction, such as clopidogrel.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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