Product image of Omnicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350) supplied by GNH India

Omnicol

Active Ingredient:
Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350
Origin:
EU

Omnicol (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Macrogol 3350, the active ingredient in Omnicol, is an osmotic laxative presented as an oral solution for oral use. It is used to relieve constipation and to prepare the bowel for diagnostic procedures in adults.

GNH India supplies Omnicol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pro Health Pharma Sweden Ab

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Indications & Clinical Uses

  • Omnicol, containing macrogol 3350 and electrolyte salts, is employed in gastrointestinal management.
  • Constipation: provides osmotic laxation to facilitate stool passage in adults.
  • Bowel preparation: cleanses the colon before colonoscopy or radiologic imaging.
  • Electrolyte replacement: restores fluid and electrolyte balance in patients with mild dehydration.

How It Works

  • Macrogol 3350 acts as an osmotic agent that retains water within the intestinal lumen, increasing stool volume and softness. The accompanying electrolytes (sodium hydrogen carbonate, potassium chloride, sodium chloride) help maintain osmotic balance and prevent significant shifts in serum electrolyte concentrations during the laxation process.

Side Effects

Common Side Effects

  • Abdominal bloating
  • Nausea
  • Flatulence
  • Diarrhea
  • Abdominal cramps
  • Headache

Serious or Rare Side Effects

  • Severe dehydration
  • Electrolyte imbalance (hypernatremia, hyperkalemia)
  • Allergic reaction (rash, itching, swelling)
  • Severe abdominal pain
  • Rectal bleeding
  • Acute renal impairment

Precautions & Warnings

  • Precautions should be observed when using Omnicol to minimize risks.
  • Assess renal function: adjust use in severe renal impairment.
  • Monitor electrolytes: avoid in patients with existing electrolyte disorders.
  • Avoid in bowel obstruction: contraindicated in mechanical blockage.
  • Use caution in elderly: increased risk of dehydration.
  • Pregnancy: limited data, use only if clearly needed.
  • Store at ambient temperature: keep in the original container, protect from moisture.

Avoid Interactions

Omnicol may interact with other medicines; awareness of major and moderate interactions is important.

Major Interactions (Avoid)

  • Sodium-containing medications: risk of hypernatremia.
  • Potassium-sparing diuretics: may cause hyperkalemia.
  • Other osmotic laxatives: additive effect leading to severe diarrhea.

Moderate Interactions (Monitor Closely)

  • Antacids: may affect absorption of electrolytes.
  • Lithium: altered renal clearance may increase toxicity.
  • ACE inhibitors: monitor potassium levels closely.

Frequently Asked Questions

Omnicol is an oral solution that combines macrogol 3350 with electrolyte salts. It is used to relieve occasional constipation, to cleanse the colon before diagnostic procedures such as colonoscopy, and to help restore fluid and electrolyte balance in patients with mild dehydration.

Macrogol 3350 is an osmotic polymer that retains water in the intestinal lumen, increasing stool volume and softness. The added electrolytes maintain osmotic equilibrium, allowing effective laxation while minimizing shifts in serum sodium, potassium, and chloride levels.

The specific dose of Omnicol is determined by the prescribing healthcare professional based on the indication, patient age, weight, and clinical condition. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Omnicol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To order Omnicol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Omnicol combines macrogol 3350 with electrolytes, offering effective osmotic laxation while helping to maintain electrolyte balance. Compared with sodium‑phosphate preparations, it generally has a lower risk of significant electrolyte disturbances, but individual patient factors and physician preference guide the choice of therapy.

Omnicol should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Ensure the container is tightly closed and keep it out of reach of children.

Omnicol is taken orally as directed by a healthcare professional. The solution is usually measured with a calibrated device and consumed with a glass of water. The exact administration schedule depends on the intended use, such as constipation relief or bowel preparation.

Serious risks include severe dehydration, significant electrolyte imbalances (such as hypernatremia or hyperkalemia), allergic reactions, and, in rare cases, acute renal impairment. Patients should be monitored for these events, especially if they have underlying kidney disease or are taking interacting medications.

Omnicol should be avoided in individuals with known mechanical bowel obstruction, severe renal impairment, uncontrolled electrolyte disorders, or hypersensitivity to any of its components. It should also be used with caution in pregnant or breastfeeding women and in the elderly, under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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