Product image of Onbrez Breezhaler (Indacaterol) supplied by GNH India

Onbrez Breezhaler

Active Ingredient:
Indacaterol
Origin:
EU

Onbrez Breezhaler (Indacaterol)

Indacaterol, the active ingredient in Onbrez Breezhaler, is a long‑acting β2‑adrenergic agonist presented as a dry‑powder inhalation formulation for inhalation use. It provides bronchodilation for adults with chronic obstructive pulmonary disease (COPD). GNH India supplies Onbrez Breezhaler as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH India supplies Onbrez Breezhaler as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Novartis Europharm Limited

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Indications & Clinical Uses

Onbrez Breezhaler contains indacaterol, a bronchodilator that acts on the airway smooth‑muscle pathway to improve airflow in chronic lung disease.

  • Chronic obstructive pulmonary disease (COPD): provides once‑daily maintenance bronchodilation and reduces exacerbation risk.
  • Stable COPD with dyspnoea: improves exercise tolerance and health‑related quality of life.
  • COPD patients inadequately controlled on short‑acting bronchodilators: offers a long‑acting alternative for symptom control.

How It Works

  • Indacaterol selectively stimulates β2‑adrenergic receptors on airway smooth muscle, activating adenylate cyclase and increasing cyclic AMP levels. The rise in cAMP leads to relaxation of bronchial smooth muscle, producing sustained bronchodilation that improves airflow and reduces airway resistance in the lungs.

Side Effects

Adverse reactions to indacaterol are reported across a range of frequencies.

Common Side Effects

  • Cough
  • Throat irritation
  • Nasopharyngitis
  • Headache
  • Dry mouth
  • Upper respiratory tract infection

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Cardiovascular events such as tachycardia or palpitations
  • Severe allergic reactions (anaphylaxis)
  • Hypersensitivity skin reactions
  • Acute COPD exacerbation
  • Pneumonia

Precautions & Warnings

When using Onbrez Breezhaler, consider the following safety measures:

  • Assess patient history: review   
  • Monitor  
  • Counsel  
  • Avoid use  
  • Store at ambient :  

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Avoid Interactions

  • Indole      
  • Major  
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Frequently Asked Questions

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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