Product image of Once-A-Day Hayfever & Allergy (Loratadine) supplied by GNH India

Once-A-Day Hayfever & Allergy

Active Ingredient:
Loratadine
Origin:
EU

Once-A-Day Hayfever & Allergy (Loratadine)

Loratadine, the active ingredient in Once-A-Day Hayfever & Allergy, is an antihistamine presented as an oral tablet for oral use. It reduces symptoms of allergic rhinitis, hay fever and urticaria in both adults and children, and is available over‑the‑counter in the European Union.

GNH India supplies Once-A-Day Hayfever & Allergy as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies, hospitals and clinics worldwide, ensuring consistent quality and regulatory compliance across markets.

Manufacturer / TM Owner

Brown & Burk Uk Limited

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Indications & Clinical Uses

  • Loratadine is an antihistamine used to manage allergic conditions affecting the nasal passages and skin.
  • Allergic rhinitis: alleviates sneezing, nasal congestion, itching and runny nose.
  • Hay fever: reduces seasonal allergy symptoms such as watery eyes and nasal discharge.
  • Urticaria: relieves itching and the formation of hives.

How It Works

  • Loratadine selectively blocks peripheral H1 histamine receptors, preventing histamine from binding to mast cells and sensory nerves. By antagonizing the H1 receptor, it inhibits the cascade that leads to vasodilation, increased vascular permeability, and nerve stimulation, thereby reducing typical allergic signs such as itching, swelling, and rhinorrhea.

Side Effects

Loratadine may cause adverse reactions, which are generally mild but can be serious in rare cases.

Common Side Effects

  • Headache
  • Dry mouth
  • Fatigue
  • Nausea

Serious or Rare Side Effects

  • Anaphylaxis (severe allergic reaction)
  • Stevens‑Johnson syndrome or other severe skin reactions
  • Hepatotoxicity (liver injury)
  • Cardiac arrhythmias or other serious heart disturbances

Precautions & Warnings

  • Before using loratadine, consider the following precautions:
  • Pregnancy: consult a healthcare provider before use.
  • Breastfeeding: use only if the benefit outweighs potential risk to the infant.
  • Renal impairment: dose adjustment may be required in severe cases.
  • Drug interactions: review all concomitant medications for possible interactions.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Loratadine can interact with several medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid)

  • Erythromycin: may increase loratadine plasma concentrations.
  • Ketoconazole: may elevate loratadine levels.
  • Ritonavir: can raise exposure to loratadine.
  • Other azole antifungals: may increase loratadine concentrations.

Moderate Interactions (Monitor Closely)

  • Theophylline: may reduce loratadine effectiveness.
  • Alcohol: may enhance drowsiness.
  • Concurrent antihistamines: may cause additive sedation.

Frequently Asked Questions

Once-A-Day Hayfever & Allergy is an over‑the‑counter antihistamine containing loratadine, indicated for relief of symptoms associated with allergic rhinitis, hay fever and chronic urticaria. It helps reduce sneezing, itching, runny nose, watery eyes and hives.

Loratadine is a selective peripheral H1‑receptor antagonist. By blocking H1 receptors on mast cells and sensory nerves, it prevents histamine‑mediated vasodilation, increased vascular permeability and nerve stimulation, thereby diminishing the typical signs of an allergic response.

The dosage is determined by the prescribing healthcare professional based on the patient’s age, condition severity and regulatory guidelines. Typically, adults and children above a certain age may receive a standard once‑daily dose, but the exact amount should follow the prescriber’s instruction.

Safety data are limited; loratadine should only be used during pregnancy or lactation if the potential benefit justifies the possible risk to the fetus or infant. Healthcare providers should evaluate individual circumstances before prescribing.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any required cold‑chain) and import documentation.

Loratadine is a second‑generation antihistamine with minimal sedation compared with first‑generation agents such as diphenhydramine. Its once‑daily dosing and favorable safety profile make it a preferred option for many patients, though efficacy is comparable across antihistamine classes for allergic symptom relief.

Store the tablets below 25 °C in their original container, protected from moisture and direct sunlight. Keep out of reach of children and do not use if the packaging is damaged. No refrigeration is required.

The tablet is taken orally with or without food, typically once a day as directed by a healthcare professional. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Although rare, serious adverse reactions can include anaphylaxis, Stevens‑Johnson syndrome, severe skin reactions, liver injury and cardiac arrhythmias. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, jaundice, or irregular heartbeat.

Loratadine is contraindicated in individuals with known hypersensitivity to loratadine or any excipients in the formulation. Caution is advised for patients with severe renal impairment, pregnant or breastfeeding women unless benefits outweigh risks, and those taking medications that may cause significant interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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