Product image of Ondansétron Viatris (Ondansetron) supplied by GNH India

Ondansétron Viatris

Active Ingredient:
Ondansetron
Origin:
EU

Ondansétron Viatris (Ondansetron)

Ondansetron, the active ingredient in Ondansétron Viatris, is a serotonin 5‑HT3 receptor antagonist presented as a tablet for oral use. It is used to prevent nausea and vomiting associated with chemotherapy, radiotherapy and postoperative recovery in adults and children.

GNH India supplies Ondansétron Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Viatris Sante

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ondansetron is employed across several clinical pathways that involve emesis control:

  • Chemotherapy‑induced nausea and vomiting (CINV): helps reduce the frequency and severity of nausea and vomiting in patients receiving moderately to highly emetogenic chemotherapy.
  • Radiotherapy‑induced nausea and vomiting (RINV): provides prophylactic relief for patients undergoing radiation treatment.
  • Post‑operative nausea and vomiting (PONV): reduces incidence of nausea and vomiting after surgical procedures.
  • Hyperemesis gravidarum (severe morning sickness): used off‑label in some regions to control persistent vomiting during pregnancy.

How It Works

  • Ondansetron selectively blocks serotonin (5‑HT3) receptors located on vagal afferent nerves in the gastrointestinal tract and in the chemoreceptor trigger zone of the brain. By inhibiting this receptor, it prevents the initiation of the vomiting reflex triggered by chemotherapy, radiation, anesthesia or other emetogenic stimuli.

Side Effects

Ondansetron is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Constipation: reduced bowel movements.
  • Diarrhoea: loose stools.
  • Fatigue: feeling of tiredness.
  • Dizziness: light‑headed sensation.

Serious or Rare Side Effects

  • QT prolongation: abnormal heart rhythm that may lead to arrhythmia.
  • Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Serotonin syndrome: rare when combined with other serotonergic agents.
  • Hepatic dysfunction: elevated liver enzymes.
  • Vision changes: blurred vision or visual disturbances.

Precautions & Warnings

Before prescribing Ondansetron, consider the following safety points:

  • Cardiac assessment: avoid use in patients with known prolonged QT interval or significant cardiac disease.
  • Electrolyte balance: correct hypokalaemia or hypomagnesemia which can predispose to arrhythmia.
  • Concomitant serotonergic drugs: monitor for signs of serotonin syndrome.
  • Liver impairment: dose adjustment may be required in moderate to severe hepatic dysfunction.
  • Pregnancy and lactation: weigh benefits against potential risks; use only if clearly needed.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ondansetron may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Apixaban, Rivaroxaban, Dabigatran: increased risk of bleeding.
  • Tramadol and other opioids: heightened risk of serotonin syndrome.
  • Amiodarone and other QT‑prolonging agents: additive effect on QT interval.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., fluconazole): may increase ondansetron plasma levels.
  • Antidepressants (SSRIs, SNRIs): potential for serotonin syndrome.
  • Anticonvulsants (carbamazepine, phenytoin): may reduce ondansetron effectiveness.

Frequently Asked Questions

Ondansétron Viatris contains ondansetron, a medication used to prevent and treat nausea and vomiting caused by chemotherapy, radiotherapy, surgery and, in some regions, severe pregnancy‑related nausea. It works by blocking the signals that trigger the vomiting reflex.

Ondansetron blocks serotonin (5‑HT3) receptors in the gastrointestinal tract and the brain’s chemoreceptor trigger zone. By preventing serotonin from activating these receptors, the drug interrupts the neural pathway that initiates vomiting, providing relief from emesis.

The dose of ondansetron is individualized by the prescribing clinician based on the indication, patient age, weight and renal or hepatic function. The prescriber determines the appropriate strength, frequency and duration of therapy.

Ondansetron is classified as pregnancy category B in the EU, indicating no evidence of fetal risk in animal studies but limited human data. It may be used during pregnancy only when the benefit outweighs potential risk, and it is excreted in breast milk, so breastfeeding mothers should consult their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ondansetron belongs to the 5‑HT3 antagonist class, offering rapid onset and effective control of both acute and delayed nausea. Compared with dopamine antagonists (e.g., metoclopramide) it has fewer extrapyramidal side effects, and unlike corticosteroids it does not cause hyperglycaemia, making it a preferred choice for many chemotherapy protocols.

Store the tablets at ambient temperature, below 25 °C, in the original container. Protect them from moisture, heat and direct sunlight to maintain potency throughout the shelf‑life.

Ondansétron Viatris is supplied as oral tablets that are swallowed whole with water. Depending on the clinical situation, the tablet may be taken with or without food, as directed by the prescribing clinician.

The most serious adverse events include QT‑interval prolongation, which can lead to potentially life‑threatening arrhythmias, and rare cases of severe allergic reactions or serotonin syndrome when combined with other serotonergic agents. Patients should be monitored for cardiac symptoms and signs of hypersensitivity.

Ondansetron is contraindicated in patients with known hypersensitivity to the drug or any of its excipients, and it should be avoided in individuals with congenital long‑QT syndrome or those taking other QT‑prolonging medications unless benefits clearly outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ondansetron

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT