Product image of Ondansetron Biogaran (Ondansetron) supplied by GNH India

Ondansetron Biogaran

Active Ingredient:
Ondansetron
Origin:
EU

Ondansetron Biogaran (Ondansetron)

Ondansetron, the active ingredient in Ondansetron Biogaran, is a 5‑HT₃ receptor antagonist presented as a medication for oral or injectable use to prevent nausea and vomiting. It is commonly employed in patients receiving chemotherapy, radiation therapy, or undergoing surgery.

GNH India supplies Ondansetron Biogaran as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, and pharmacies worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches for global distribution.

Manufacturer / TM Owner

Biogaran

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ondansetron is used to control nausea and vomiting associated with several therapeutic pathways.

  • Chemotherapy‑induced nausea and vomiting: reduces acute and delayed episodes in cancer patients receiving emetogenic chemotherapy.
  • Radiation‑induced nausea and vomiting: prevents nausea during and after radiotherapy to the abdomen or pelvis.
  • Postoperative nausea and vomiting: decreases incidence of nausea and vomiting after surgical procedures.

How It Works

  • Ondansetron selectively blocks serotonin (5‑HT₃) receptors located on vagal afferent nerves in the gastrointestinal tract and in the chemoreceptor trigger zone of the brain. By inhibiting the binding of serotonin released during chemotherapy, radiation, or surgical stress, it prevents the neural signaling that initiates the vomiting reflex.

Side Effects

Ondansetron may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Constipation: reduced bowel movements.
  • Diarrhoea: loose stools.
  • Fatigue: feeling of tiredness.
  • Dizziness: transient light‑headedness.

Serious or Rare Side Effects

  • QT interval prolongation: may lead to cardiac arrhythmias.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Serotonin syndrome: agitation, hyperreflexia, fever (rare when combined with serotonergic agents).

Precautions & Warnings

When prescribing ondansetron, clinicians should consider several safety measures.

  • Cardiac monitoring: assess baseline ECG in patients with known QT prolongation.
  • Electrolyte balance: correct hypokalemia or hypomagnesemia before use.
  • Drug interactions: review concomitant medications that affect cardiac conduction.
  • Pregnancy: use only if potential benefit justifies risk; discuss with obstetrician.
  • Breastfeeding: limited data; weigh benefits against possible infant exposure.
  • Store at room temperature: keep below 25 °C, protect from moisture and light in original packaging.

Avoid Interactions

Ondansetron can interact with other medicines, influencing efficacy or safety.

Major Interactions (Avoid)

  • Amiodarone: combined use may markedly increase QT prolongation risk.
  • Certain antiarrhythmics (e.g., sotalol, quinidine): additive effect on cardiac repolarization.
  • Tricyclic antidepressants (e.g., amitriptyline): may enhance QT interval changes.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (e.g., ketoconazole, fluconazole): can raise ondansetron plasma levels.
  • Antiemetics with serotonergic activity (e.g., granisetron): potential for serotonin syndrome.
  • CYP3A4 inhibitors (e.g., erythromycin): may increase exposure, monitor for side effects.

Frequently Asked Questions

Ondansetron Biogaran is used to prevent and treat nausea and vomiting caused by chemotherapy, radiation therapy, and postoperative recovery. It is a 5‑HT₃ receptor antagonist that helps control these symptoms in adult patients undergoing such treatments.

Ondansetron works by selectively blocking serotonin (5‑HT₃) receptors in the gastrointestinal tract and the brain’s chemoreceptor trigger zone. This inhibition stops serotonin‑mediated signaling that would otherwise trigger the vomiting reflex.

The specific dose of ondansetron is determined by the prescribing healthcare professional based on the indication, patient age, weight, and clinical condition. Dosage regimens vary for chemotherapy, radiation, and postoperative settings.

Ondansetron should be used in pregnancy only if the potential benefit outweighs any risk to the fetus, and it is prescribed after careful consideration by the obstetrician. Limited data are available for breastfeeding; the decision should balance maternal benefit against possible infant exposure.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and necessary import documentation.

Ondansetron belongs to the 5‑HT₃ antagonist class, offering a targeted mechanism that differs from dopamine antagonists (e.g., metoclopramide) and antihistamines (e.g., diphenhydramine). It is generally preferred for chemotherapy‑induced nausea due to its efficacy and lower risk of extrapyramidal side effects.

Store Ondansetron Biogaran at room temperature, below 25 °C, in its original packaging. Protect it from moisture and direct light. Do not refrigerate unless the specific dosage form indicates otherwise.

Ondansetron can be administered orally as tablets or liquid, or intravenously/ intramuscularly depending on the product formulation. The route of administration is selected by the prescriber according to the clinical situation and patient needs.

The most serious risks include QT interval prolongation, which can lead to potentially life‑threatening cardiac arrhythmias, and rare severe allergic reactions such as anaphylaxis. Monitoring ECG and electrolyte status is recommended for patients at risk.

Ondansetron should be avoided in patients with known hypersensitivity to the drug or any component of the formulation, and in individuals with congenital long QT syndrome or significant electrolyte disturbances unless corrected. Caution is also advised for patients on other QT‑prolonging medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ondansetron

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT