Product image of Onnimia (Fulvestrant) supplied by GNH India

Onnimia

Active Ingredient:
Fulvestrant
Origin:
EU

Onnimia (Fulvestrant)

Fulvestrant, the active ingredient in Onnimia, is a selective estrogen receptor degrader presented as a 250 mg/mL solution for intramuscular injection use. It treats hormone receptor‑positive metastatic breast cancer in post‑menopausal women. GNH India supplies Onnimia as a licensed, GDP‑compliant international pharmaceutical supplier serving oncology centres, hospitals and pharmacies worldwide.

GNH India supplies Onnimia as a licensed, GDP‑compliant international pharmaceutical supplier serving oncology centres, hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Adamed Laboratorios S.L.U.

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Indications & Clinical Uses

Onnimia is a selective estrogen receptor degrader that targets hormone‑driven breast cancer pathways.

  • Metastatic breast cancer: Improves progression‑free survival in post‑menopausal women with estrogen‑receptor‑positive disease.
  • Hormone‑responsive tumors: Reduces tumor growth by degrading estrogen receptors.
  • Advanced disease after endocrine therapy: Provides an alternative mechanism when prior endocrine agents have failed.

How It Works

  • Fulvestrant binds with high affinity to estrogen receptors (ERα and ERH) in breast cancer cells, causing receptor dimerisation ‑ a non‑functional complex ‑ and promotes their ubiquitination and proteasomal degradation. This eliminates estrogen‑driven signaling, halting cellular proliferation and the growth of hormone‑dependent tumors.

Side Effects

Common Side Effects

  • Injection site pain
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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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