Product image of Ontipria (Tiotropium Bromide) supplied by GNH India

Ontipria

Active Ingredient:
Tiotropium Bromide
Origin:
EU

Ontipria (Tiotropium Bromide)

Tiotropium bromide, the active ingredient in Ontipria, is a long‑acting muscarinic antagonist presented as a inhalation powder for oral inhalation use. It is indicated for maintenance therapy in patients with chronic obstructive pulmonary disease, helping to improve lung function and reduce exacerbations. GNH India supplies Ontipria as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH India supplies Ontipria as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Zentiva, K.S.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ontipria is a bronchodilator that acts on the airways of patients with chronic obstructive pulmonary disease.

  • Chronic obstructive pulmonary disease (COPD): Improves airflow and reduces the frequency of exacerbations.
  • Asthma (as add‑on therapy): Provides additional bronchodilation when standard inhaled therapies are insufficient.
  • Chronic bronchitis: Helps to ease breathing difficulty associated with persistent airway inflammation.

How It Works

  • Tiotropium bromide selectively blocks muscarinic M3 receptors in the airway smooth muscle, preventing acetylcholine‑induced bronchoconstriction. This long‑acting antagonism leads to sustained bronchodilation, improved airway calibre, and reduced airway resistance over 24 hours, supporting better respiratory function in chronic obstructive airway disease.

Side Effects

Adverse reactions to Ontipria are generally mild to moderate and vary with individual sensitivity.

Common Side Effects

  • Dry mouth
  • Cough
  • Throat irritation
  • Upper respiratory tract infection
  • Headache
  • Nasal congestion

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe allergic reaction (anaphylaxis)
  • Angio‑ema
  • Persistent urinary retention
  • Tachycardia
  • Worsening of glaucoma

Precautions & Warnings

When using Ontipria, certain precautions should be observed to ensure safety and effectiveness.

  • Assess respiratory status: Perform baseline lung function testing before initiating therapy.
  • Monitor for urinary retention: Patients with prostate enlargement should be observed for difficulty voiding.
  • Evaluate glaucoma risk: Use cautiously in patients with narrow‑angle glaucoma.
  • Review concomitant medications: Check for other anticholinergic agents that may increase anticholinergic load.
  • Store at ambient temperature: Keep below 25°C, protect from moisture and keep in original packaging.

Avoid Interactions

Ontipria may interact with other medicines that influence anticholinergic activity or respiratory function. Major Interactions (Avoid):\n- Other long‑acting anticholinergics: Combined use can increase risk of severe anticholinergic effects.

  • Beta‑agonist inhalers in high doses: May potentiate cardiovascular side effects.

Moderate Interactions (Monitor Closely)

  • Antihistamines and tricyclic antidepressants: May add to dry‑mouth and urinary‑retention effects.
  • Theophylline: Requires monitoring of respiratory status and possible dose adjustment.
  • Ketamine: Potential for additive bronchodilatory effects.
  • Inhaled corticosteroids: May increase local irritation but are generally safe together.

Frequently Asked Questions

Ontipria contains tiotropium bromide, a long‑acting muscarinic antagonist that is prescribed for maintenance treatment of chronic obstructive pulmonary disease (COPD). It helps keep the airways open, reduces breathlessness, and lowers the risk of disease‑related flare‑ups.

Tiotropium bromide selectively blocks M3 muscarinic receptors on airway smooth‑muscle cells, preventing acetylcholine‑induced constriction. This inhibition produces sustained bronchodilation for up to 24 hours, improving airflow and reducing airway resistance in patients with chronic obstructive airway disease.

The prescribed dose of Ontipria is determined by a qualified healthcare professional based on the patient’s condition, age, and response to therapy. The prescriber will select the appropriate inhalation strength and dosing schedule according to clinical guidelines.

Safety data for tiotropium bromide in pregnancy are limited. It should only be used if the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consult their physician, as small amounts may be excreted in milk.

To order Ontipria, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ontipria (tiotropium) is a long‑acting anticholinergic, offering once‑daily dosing and sustained bronchodilation. Compared with short‑acting agents, it provides more consistent airway support, and unlike some long‑acting beta‑agonists, it has a different mechanism that can be combined for additive effect when needed.

Store Ontipria at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the inhaler device clean and follow the manufacturer’s instructions for cartridge replacement.

Ontipria is delivered via a dry‑powder inhaler. The patient inhales a measured dose of powder through the mouthpiece, typically once daily, after exhaling fully and sealing lips around the device. Proper inhalation technique is essential for optimal drug delivery.

Serious adverse events, although rare, include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, and acute urinary retention. Patients should seek immediate medical attention if they experience sudden breathing difficulty, swelling of the face or throat, or inability to urinate.

Ontipria is contraindicated in individuals with a known hypersensitivity to tiotropium bromide or any inhaler components. Caution is advised for patients with narrow‑angle glaucoma, significant urinary retention, or those taking other anticholinergic medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.