Product image of Oparta (Beclometasone Dipropionate, Formoterol Fumarate Dihydrate) supplied by GNH India

Oparta

Active Ingredient:
Beclometasone Dipropionate, Formoterol Fumarate Dihydrate
Origin:
EU

Oparta (Beclometasone Dipropionate, Formoterol Fumarate Dihydrate)

Beclometasone dipropionate, the active ingredient in Oparta, is a corticosteroid presented as a combination inhalation product for respiratory use. It treats asthma and chronic obstructive pulmonary disease (COPD) in adults and adolescents. GNH India supplies Oparta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH India supplies Oparta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Oparta combines an inhaled corticosteroid with a long‑acting β2‑agonist to manage chronic airway disease.

  • Asthma: improves control and reduces the frequency of exacerbations.
  • Chronic obstructive pulmonary disease (COPD): enhances lung function and lowers the risk of flare‑ups.
  • Exercise‑induced bronchoconstriction: provides pre‑exercise relief of airway narrowing.

How It Works

  • Beclometasone dipropionate binds to glucocorticoid receptors in airway cells, reducing inflammation and cytokine production. Formoterol fumarate dihydrate activates β2‑adrenergic receptors, causing smooth‑muscle relaxation and bronchodilation, together delivering anti‑inflammatory and bronchodilatory effects in the lungs.

Side Effects

Adverse reactions may appear after inhalation of Oparta.

Common Side Effects

  • Hoarseness or voice change
  • Oral thrush (candidiasis)
  • Cough or throat irritation
  • Headache
  • Nasal congestion
  • Upper respiratory tract infection

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe allergic reaction (anaphylaxis)
  • Pneumonia
  • Decreased bone mineral density with long‑term use
  • Glaucoma or cataract development
  • Adrenal suppression

Precautions & Warnings

Before using Oparta, consider the following safety points.

  • Assess asthma or COPD severity: ensure the product matches the prescribed step‑wise treatment plan.
  • Monitor for oral candidiasis: rinse mouth after each inhalation.\n- Review concomitant medications: avoid duplicate bronchodilator therapy.
  • Evaluate risk of systemic corticosteroid effects: use lowest effective dose.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Oparta may interact with other medicines; awareness helps maintain safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase systemic corticosteroid exposure.

Moderate Interactions (Monitor Closely)

  • β‑adrenergic agonists (short‑acting): additive bronchodilator effect may increase heart rate.
  • Diuretics (e.g., furosemide): may enhance hypokalaemia risk when combined with β2‑agonists.
  • Theophylline: potential for increased tremor or tachycardia.
  • Anticholinergic inhalers: monitor for overlapping respiratory effects.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): watch for heightened bronchospasm risk.

Frequently Asked Questions

Oparta is a fixed‑dose inhalation product that combines beclometasone dipropionate, an inhaled corticosteroid, with formoterol fumarate, a long‑acting β2‑agonist. It is prescribed to improve control of asthma and to maintain lung function in chronic obstructive pulmonary disease (COPD) by reducing inflammation and providing sustained bronchodilation.

Beclometasone dipropionate binds to glucocorticoid receptors in airway epithelial cells, suppressing the release of inflammatory mediators such as cytokines and chemokines. This anti‑inflammatory action decreases airway swelling, mucus production, and hyper‑responsiveness, helping to keep the airways open and less reactive.

The prescribed dose of Oparta is determined by the treating physician based on the severity of asthma or COPD, patient age, and response to therapy. Dosage instructions are individualized and should be followed exactly as written on the prescription label.

Safety data for Oparta in pregnancy are limited; it should only be used if the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consult their healthcare provider, as small amounts of inhaled corticosteroid may pass into breast milk, but the clinical significance is generally considered low.

To request Oparta, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Oparta combines an inhaled corticosteroid with a long‑acting β2‑agonist in a single device, similar to other combination inhalers such as fluticasone/salmeterol. Its specific strengths, particle size and formulation may offer different lung deposition characteristics, but clinical efficacy in controlling asthma and COPD is comparable when used as directed.

Store Oparta at ambient temperature, below 25 °C, in the original packaging to protect it from moisture and direct sunlight. Keep the inhaler cap closed when not in use and avoid exposing it to extreme temperatures that could affect the dose consistency.

Oparta is delivered via a metered‑dose inhaler. The patient inhales a prescribed number of puffs, usually after shaking the device, exhaling fully, and then breathing in slowly and deeply through the mouthpiece, followed by a breath hold for a few seconds. Specific technique instructions are provided by the prescriber.

Serious risks include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, pneumonia, and systemic effects from prolonged corticosteroid exposure like adrenal suppression, osteoporosis, glaucoma, or cataracts. Patients should seek immediate medical attention if they experience sudden breathing difficulty, swelling, or rash.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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