Product image of Ophenic (Octenidine Dihydrochloride, Phenoxyethanol) supplied by GNH India

Ophenic

Active Ingredient:
Octenidine Dihydrochloride, Phenoxyethanol
Origin:
EU

Ophenic (Octenidine Dihydrochloride, Phenoxyethanol)

Octenidine dihydrochloride, the active ingredient in Ophenic, is an antiseptic presented as a cutaneous preparation for external use. It is employed to reduce microbial load on skin and mucous membranes in hospital and clinical settings. GNH India supplies Ophenic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

GNH India supplies Ophenic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

Manufacturer / TM Owner

Schülke & Mayr Gmbh

1
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Indications & Clinical Uses

Ophenic is an antiseptic that acts on a broad spectrum of bacteria, fungi and viruses on the skin.

  • Surgical site preparation: helps prevent post‑operative infection by reducing skin flora before incision.
  • Wound care: supports maintenance of a clean wound environment to aid healing.
  • Catheter insertion sites: lowers microbial colonisation at entry points to reduce infection risk.
  • Skin decontamination: used for general pre‑procedural skin cleansing before diagnostic or therapeutic procedures.

How It Works

  • Octenidine dihydrochloride disrupts microbial cell membranes by interacting with phospholipid components, leading to loss of membrane integrity and rapid cell death. Phenoxyethanol acts as a preservative and contributes additional antimicrobial activity, enhancing the overall antiseptic effect without relying on systemic absorption.

Side Effects

Adverse reactions to Ophenic are generally limited to local skin responses.

Common Side Effects

  • Mild erythema: temporary redness at the application site.
  • Pruritus: mild itching that resolves without treatment.
  • Dryness: slight skin dryness or flaking.
  • Sensation of burning: brief mild burning feeling on contact.

Serious or Rare Side Effects

  • Contact dermatitis: pronounced inflammation, vesicles or swelling requiring medical attention.
  • Allergic reaction: hives, angio‑oedema or systemic urticaria.
  • Severe skin necrosis: tissue breakdown at the site of application.
  • Anaphylaxis: life‑threatening systemic reaction needing emergency care.

Precautions & Warnings

When using Ophenic, follow standard antiseptic safety practices.

  • Avoid: Use the product only in the intended cutaneous application area.
  • Monitor: Observe the application site for signs of irritation or allergic response.
  • Contraindicate: Do not apply on open wounds with exposed deep tissue.\nStore at ambient temperature: keep the vial in its original pack and protect from moisture.

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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