Product image of Ophtesic (Anhydrous Lidocaine Hydrochloride) supplied by GNH India

Ophtesic

Active Ingredient:
Anhydrous Lidocaine Hydrochloride
Origin:
EU

Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Ophtesic, is a local anesthetic presented as a sterile ophthalmic solution for topical ocular use. It provides rapid surface numbness to facilitate diagnostic examinations and minor eye procedures.
GNH India supplies Ophtesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Doliage Developpement

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Indications & Clinical Uses

Ophtesic, a lidocaine‑based ocular anesthetic, is used to provide temporary surface anesthesia for various eye procedures.

  • Diagnostic eye examinations: numbs the ocular surface to allow comfortable slit‑lamp biomicroscopy.
  • Minor ocular surgery: facilitates painless corneal scraping, foreign‑body removal, or incision.
  • Laser procedures: reduces discomfort during laser photocoagulation or iridotomy.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels in neuronal membranes, preventing the initiation and propagation of action potentials. By stabilizing the neuronal membrane, it inhibits the transmission of pain signals from the ocular surface, resulting in rapid and reversible loss of sensation in the treated area.

Side Effects

Adverse reactions may occur following ocular administration of lidocaine.

Common Side Effects

  • Transient burning or stinging sensation at the application site.
  • Mild ocular irritation or redness.
  • Temporary blurred vision.
  • Excessive tearing (epiphora).
  • Mild conjunctival hyperemia.

Serious or Rare Side Effects

  • Allergic reactions such as angioedema or anaphylaxis.
  • Corneal epithelial toxicity or ulceration.
  • Increased intra‑ocular pressure.
  • Persistent corneal ulceration or infection.
  • Severe ocular inflammation.
  • Systemic toxicity (e.g., CNS symptoms) in cases of overdose.

Precautions & Warnings

Careful assessment and monitoring are required when using Ophtesic.

  • Allergy assessment: avoid if the patient has known hypersensitivity to amide‑type anesthetics.
  • Corneal integrity: use with caution on compromised corneas or epithelial defects.
  • Contact lens wearers: remove lenses before administration to prevent drug retention.
  • Systemic absorption: limit use in patients with severe cardiac conduction disorders.
  • Pregnancy and lactation: evaluate risk–benefit and use only if essential.
  • Store below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Lidocaine may interact with other medications affecting cardiac conduction or metabolism.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine, procainamide): may increase systemic lidocaine levels.
  • Beta‑blockers: potential additive effects on cardiac conduction.

Moderate Interactions (Monitor Closely)

  • Concurrent use of other local anesthetics: risk of cumulative toxicity.
  • CYP3A4 inhibitors (e.g., erythromycin): may alter lidocaine metabolism.
  • Systemic vasoconstrictors: may affect ocular blood flow and drug distribution.

Frequently Asked Questions

Ophtesic is a lidocaine‑based ophthalmic solution used to provide temporary surface anesthesia for diagnostic eye examinations, minor ocular surgeries, and laser procedures. It numbs the ocular surface, allowing clinicians to perform procedures with reduced patient discomfort.

Lidocaine blocks voltage‑gated sodium channels on sensory nerve fibers in the eye, preventing the initiation and propagation of pain signals. This stabilizes neuronal membranes and produces rapid, reversible loss of sensation on the ocular surface.

The specific dose and administration schedule for Ophtesic are determined by the prescribing clinician based on the procedure, patient characteristics, and clinical judgment. Healthcare professionals should follow the product labeling and institutional protocols.

Safety data for lidocaine ophthalmic use in pregnancy and lactation are limited. The drug should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the prescriber should evaluate each case individually.

To request Ophtesic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and import documentation.

Ophtesic contains lidocaine, an amide‑type local anesthetic with a rapid onset and short duration, similar to other lidocaine‑based eye drops. Compared with proparacaine or tetracaine, lidocaine offers comparable efficacy but may have a slightly different safety profile regarding corneal toxicity, making choice dependent on clinician preference and patient factors.

Ophtesic should be stored below 25 °C in its original container, protected from moisture and light. Do not freeze the product. Once opened, use according to the label’s recommended period to maintain sterility and potency.

Ophtesic is applied topically to the ocular surface as a sterile drop. The prescriber determines the number of drops and timing based on the intended procedure. Proper aseptic technique should be used to avoid contamination.

Serious risks include allergic reactions such as angioedema or anaphylaxis, corneal epithelial toxicity leading to ulceration, and systemic toxicity if excessive amounts are absorbed. Patients should be monitored for signs of severe irritation, visual changes, or systemic symptoms.

Ophtesic should not be used in individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, in eyes with active severe infection, or in patients with compromised corneal epithelium where further toxicity could be detrimental.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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