Product image of Ophtesic (Anhydrous Lidocaine Hydrochloride) supplied by GNH India

Ophtesic

Active Ingredient:
Anhydrous Lidocaine Hydrochloride
Origin:
EU

Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine hydrochloride, the active ingredient in Ophtesic, is a local anesthetic presented as a topical solution for ocular use. It provides topical ocular anesthesia for diagnostic or therapeutic procedures and relief of ocular surface pain.

GNH India supplies Ophtesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Doliage Developpement

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Indications & Clinical Uses

Ophtesic (lidocaine hydrochloride) is used as a topical ocular anesthetic for procedures involving the eye surface.

  • Diagnostic ocular procedures: provides anesthesia to facilitate examination and testing.
  • Therapeutic ocular procedures: enables painless administration of treatments such as laser therapy.
  • Ocular surface pain: relieves discomfort from corneal abrasions, foreign bodies or postoperative irritation.

How It Works

  • Lidocaine hydrochloride blocks voltage‑gated sodium channels in neuronal membranes of ocular surface nerves, preventing the initiation and propagation of action potentials. This inhibition of nerve impulse conduction produces a rapid, reversible loss of sensation, delivering local anesthesia to the eye without affecting systemic nerve function.

Side Effects

Common Side Effects

  • Transient burning sensation at the application site.
  • Mild stinging or itching.
  • Temporary blurred vision.
  • Tear film disturbance or increased tearing.
  • Mild conjunctival hyperemia.
  • Slight eyelid edema.

Serious or Rare Side Effects

  • Corneal epithelial toxicity or ulceration.
  • Allergic contact dermatitis of the eyelid or conjunctiva.
  • Severe ocular inflammation or uveitis.
  • Vision loss (rare).
  • Persistent epithelial defect.
  • Systemic signs of lidocaine toxicity (very rare).

Precautions & Warnings

Before using Ophtesic, consider the following precautions:

  • Allergy assessment: verify no known hypersensitivity to lidocaine or amide anesthetics.
  • Eye condition: avoid use in infected, inflamed, or compromised ocular surfaces unless directed by a clinician.
  • Contact lens: remove contact lenses prior to administration.
  • Systemic absorption: limit use in patients with severe cardiac conduction disorders.
  • Pregnancy and lactation: use only if the expected benefit outweighs potential risk; consult the prescriber.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Lidocaine hydrochloride may interact with other agents when used ocularly.

Major Interactions (Avoid)

  • Systemic local anesthetics: concurrent use may increase plasma lidocaine levels.
  • Class I antiarrhythmic drugs (e.g., quinidine): additive cardiac effects.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may potentiate bradycardia if systemic absorption occurs.
  • CYP3A4 inhibitors: may affect metabolism of systemically absorbed lidocaine.
  • Other ophthalmic solutions: may alter drug absorption or cause formulation incompatibility.

Frequently Asked Questions

Ophtesic is a lidocaine‑based ophthalmic solution used to provide local anesthesia for diagnostic eye examinations, therapeutic ocular procedures, and to relieve discomfort from ocular surface pain such as corneal abrasions or postoperative irritation.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on sensory nerve endings of the eye. By preventing sodium influx, it stops the generation and propagation of nerve impulses, resulting in rapid, reversible loss of sensation in the ocular surface.

The appropriate dose of Ophtesic is determined by the prescribing clinician based on the specific procedure, patient age, and clinical setting. The prescriber will specify the volume and frequency of application required for each individual case.

Safety data for Ophtesic in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare professional.

To order Ophtesic, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and import documentation.

Ophtesic contains lidocaine, an amide‑type local anesthetic with a rapid onset and short duration, making it suitable for brief procedures. Compared with ester‑type agents such as proparacaine, lidocaine generally offers a slightly longer duration of anesthesia but a similar safety profile when used correctly.

Ophtesic should be stored at room temperature, below 25 °C, in its original packaging. Protect the container from direct sunlight, moisture, and extreme temperature fluctuations to maintain product stability.

Ophtesic is applied topically to the ocular surface as a drop or a small amount of solution, as directed by the clinician. The eye should be gently closed after administration to allow adequate absorption, and contact lenses should be removed beforehand.

Serious risks, though rare, include corneal epithelial toxicity, severe allergic reactions such as contact dermatitis, and, in cases of significant systemic absorption, signs of lidocaine toxicity like cardiac arrhythmias or central nervous system effects.

Ophtesic should be avoided in individuals with known hypersensitivity to lidocaine or other amide local anesthetics, in eyes with active infection or severe inflammation unless specifically indicated, and in patients with certain cardiac conduction disorders where systemic absorption could pose a risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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