Product image of Ophtesic (Anhydrous Lidocaine Hydrochloride) supplied by GNH India

Ophtesic

Active Ingredient:
Anhydrous Lidocaine Hydrochloride
Origin:
EU

Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine hydrochloride, the active ingredient in Ophtesic, is a local anesthetic presented as a sterile ophthalmic solution for ocular use. It provides temporary loss of sensation on the surface of the eye, facilitating diagnostic and minor surgical procedures.

GNH India supplies Ophtesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Doliage Developpement

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Indications & Clinical Uses

Ophtesic, a lidocaine‑based ophthalmic anesthetic, is employed for procedures involving the ocular surface and anterior segment.

  • Corneal anesthesia: enables painless examination and removal of corneal foreign bodies.
  • Intra‑ocular surgery preparation: provides local numbness before cataract or laser procedures.
  • Conjunctival surgery: facilitates comfortable excision of lesions or biopsies.
  • Diagnostic testing: allows patient comfort during tonometry or fluorescein staining.

How It Works

  • Lidocaine hydrochloride blocks voltage‑gated sodium channels in neuronal membranes of ocular sensory nerves, preventing the initiation and propagation of action potentials. This inhibition halts nerve impulse conduction, resulting in localized loss of sensation on the ocular surface without affecting systemic nerve function.

Side Effects

Adverse reactions may occur following ocular administration of lidocaine.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Temporary blurred vision.
  • Redness of the conjunctiva.
  • Mild tearing or lacrimation.
  • Sensation of foreign body in the eye.

Serious or Rare Side Effects

  • Corneal epithelial toxicity or ulceration.
  • Severe allergic reaction (e.g., angioedema, anaphylaxis).
  • Persistent intra‑ocular pressure elevation.
  • Endophthalmitis or intra‑ocular infection.
  • Vision loss unrelated to the underlying procedure.

Precautions & Warnings

When using Ophtesic, consider the following safety measures.

  • Patient assessment: evaluate for known lidocaine allergy before administration.
  • Ocular condition: avoid use on compromised corneal epithelium or active infections.
  • Dosage control: apply only the amount prescribed to limit systemic absorption.
  • Monitoring: observe for signs of toxicity, especially in pediatric or elderly patients.
  • Storage: Store at below 25°C: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaine ophthalmic solutions may interact with certain systemic or topical agents.

Major Interactions (Avoid)

  • Systemic local anesthetics: concurrent use may increase risk of systemic toxicity.
  • Monoamine oxidase inhibitors (MAOIs): may potentiate cardiovascular effects.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: monitor for additive bradycardia if systemic absorption occurs.
  • Anticholinergic ophthalmic agents: may affect pupil size and intra‑ocular pressure.
  • CYP450 substrates: lidocaine is metabolized by CYP3A4; monitor levels of drugs with narrow therapeutic windows.

Frequently Asked Questions

Ophtesic is an ophthalmic solution containing lidocaine hydrochloride that provides local anesthesia to the eye. It is used to numb the ocular surface during diagnostic examinations, removal of foreign bodies, and minor surgical or laser procedures involving the cornea or conjunctiva.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on sensory nerves in the eye. By preventing the influx of sodium ions, it stops the generation and transmission of nerve impulses, resulting in temporary loss of sensation on the ocular surface.

The specific dose and frequency of Ophtesic are determined by the prescribing clinician based on the procedure and patient factors. Healthcare professionals should follow the product label and clinical guidelines when administering the solution.

Safety data for lidocaine ophthalmic solutions in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To order Ophtesic, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Ophtesic uses lidocaine, a well‑established local anesthetic with rapid onset and short duration, similar to other ophthalmic agents such as proparacaine or tetracaine. Choice of agent depends on the procedure, desired duration of anesthesia, and individual patient tolerance.

Ophtesic should be stored at temperatures below 25 °C, in its original container, protected from light and moisture. Do not freeze the solution, and keep it out of reach of children.

Ophtesic is applied topically to the eye as a sterile drop. The prescriber determines the number of drops and timing relative to the procedure. Proper aseptic technique should be used to avoid contamination.

Serious risks, though rare, include corneal toxicity, severe allergic reactions such as anaphylaxis, and intra‑ocular infection (endophthalmitis). Immediate medical attention is required if signs of a serious reaction develop.

Ophtesic should not be used in patients with a known hypersensitivity to lidocaine or other amide‑type local anesthetics, or on eyes with active infections, severe epithelial defects, or compromised corneal integrity unless specifically directed by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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