Product image of Ophtesic (Anhydrous Lidocaine Hydrochloride) supplied by GNH India

Ophtesic

Active Ingredient:
Anhydrous Lidocaine Hydrochloride
Origin:
EU

Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Ophtesic, is a local anesthetic presented as a sterile ophthalmic solution for topical ocular use. It provides rapid, reversible numbness of the cornea and conjunctiva, facilitating pain‑free examinations and minor procedures in patients of all ages.

GNH India supplies Ophtesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for export to multiple regions. Customers benefit from reliable logistics, batch traceability, and responsive technical support throughout the supply chain.

Manufacturer / TM Owner

Laboratoires Doliage Developpement

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Indications & Clinical Uses

Ophtesic, containing lidocaine, provides topical anesthesia for ocular surface procedures and examinations.

  • Corneal abrasion: relieves pain and discomfort during healing.
  • Intra‑ocular surgery: numbs the ocular surface to facilitate safe instrument insertion.
  • Diagnostic eye examinations: reduces stinging from fluorescein staining and other diagnostic agents.

How It Works

  • Lidocaine exerts its effect by reversibly blocking voltage‑gated sodium channels in neuronal membranes of the corneal and conjunctival nerves. This inhibition prevents the initiation and propagation of action potentials, leading to a temporary loss of sensory transmission. The blockade is concentration‑dependent and rapidly reversible, allowing quick onset of anesthesia with a short duration after the drug is removed.

Side Effects

Adverse ocular reactions to Ophtesic are generally mild, but rare serious events can occur.

Common Side Effects

  • Stinging or burning sensation upon instillation.
  • Transient blurred vision.
  • Conjunctival hyperemia.
  • Excessive tearing.

Serious or Rare Side Effects

  • Allergic reaction with eyelid edema or angioedema.
  • Corneal epithelial damage.
  • Increased intra‑ocular pressure.
  • Systemic toxicity presenting as CNS symptoms such as dizziness or seizures.

Precautions & Warnings

Before using Ophtesic, consider the following precautions to ensure safe and effective application.

  • Allergy assessment: avoid in patients with known lidocaine hypersensitivity.
  • Ocular infection: defer use until active infection has been treated.
  • Contact lens wearers: remove lenses prior to instillation and wait before reinserting.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk.
  • Pediatric use: dosage and frequency should be determined by an ophthalmologist.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Ophtesic may interact with certain systemic and topical agents; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Class I antiarrhythmic drugs (e.g., quinidine, procainamide): risk of additive cardiotoxicity.
  • Concurrent use of other local anesthetics: potential for cumulative lidocaine toxicity.
  • Systemic central nervous system depressants (e.g., barbiturates, benzodiazepines): enhanced CNS depression.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask early signs of lidocaine toxicity.
  • Calcium channel blockers: can increase plasma lidocaine concentrations.
  • Epinephrine‑containing ophthalmic solutions: may alter lidocaine absorption and prolong effect.

Frequently Asked Questions

Ophtesic is an ophthalmic preparation containing lidocaine that provides local anesthesia to the surface of the eye. It is used to relieve pain from corneal abrasions, to numb the ocular surface before minor surgical or diagnostic procedures, and to reduce discomfort during fluorescein staining or other eye examinations.

Lidocaine works by reversibly blocking voltage‑gated sodium channels on sensory nerve fibers in the cornea and conjunctiva. This blockade stops the initiation and propagation of nerve impulses, producing a temporary loss of sensation. The effect is concentration‑dependent, rapid in onset, and wears off shortly after the drug is cleared from the ocular surface.

The specific dose and frequency of Ophtesic are determined by the prescribing ophthalmologist based on the procedure and patient characteristics. Typically, a few drops are instilled onto the ocular surface shortly before the intended examination or intervention, but exact regimens should follow the clinician’s written instructions.

Safety data for lidocaine ophthalmic use in pregnancy and lactation are limited. Ophtesic should be used only if the potential therapeutic benefit justifies any potential risk to the fetus or infant. The prescriber should evaluate the individual situation and discuss possible alternatives when appropriate.

To place an order, submit an enquiry on the Ophtesic product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Ophtesic delivers lidocaine, a well‑studied amide‑type local anesthetic with a rapid onset and short duration, making it suitable for brief procedures. Compared with ester‑type agents such as proparacaine, lidocaine generally provides a slightly longer anesthetic window and a comparable safety profile, though individual patient response may vary.

Ophtesic should be stored at room temperature, below 25 °C, in its original sealed container. Protect the product from direct sunlight, excessive heat and moisture. Once opened, use the solution within the period recommended by the manufacturer and discard any remaining product after that time.

Ophtesic is applied as sterile eye drops. The prescriber or trained healthcare professional instills the recommended number of drops onto the conjunctival sac, typically a few minutes before the intended procedure. Patients should be instructed not to touch the dropper tip to the eye or any surface to maintain sterility.

Serious risks, although rare, include allergic reactions such as eyelid edema or angioedema, corneal epithelial injury, and systemic lidocaine toxicity that can manifest as central nervous system symptoms (e.g., dizziness, seizures) or cardiovascular effects. Prompt medical attention is required if any of these events occur.

Ophtesic should be avoided in individuals with a known hypersensitivity to lidocaine or any other component of the formulation. It is also contraindicated in patients with active ocular infections that have not been treated, and it should be used with caution in pregnant or breastfeeding women, children, and those on interacting systemic medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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