Product image of Ophtesic (Anhydrous Lidocaine Hydrochloride) supplied by GNH India

Ophtesic

Active Ingredient:
Anhydrous Lidocaine Hydrochloride
Origin:
EU

Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Ophtesic, is a local anesthetic presented as a sterile ophthalmic solution for ocular use. It provides topical anesthesia for diagnostic or minor surgical procedures on the eye.

GNH India supplies Ophtesic as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Doliage Developpement

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Indications & Clinical Uses

Ophtesic, a lidocaine-based ophthalmic anesthetic, is used to provide temporary loss of sensation in ocular tissues.

  • Diagnostic ocular examinations: provides anesthesia for slit‑lamp biomicroscopy, tonometry and other assessments.
  • Minor ocular surgery: facilitates procedures such as foreign body removal, laser treatment and small incisions.
  • Contact lens fitting: reduces discomfort during lens insertion and adjustment.

How It Works

  • Lidocaine Hydrochloride produces reversible blockade of voltage‑gated sodium channels on neuronal membranes, inhibiting the initiation and propagation of nerve impulses. This interruption of sodium influx prevents depolarization, resulting in localized loss of sensation in the ocular surface where the drug is applied.

Side Effects

Ophtesic may cause a range of ocular reactions, most of which are mild and transient.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Transient redness of the conjunctiva.
  • Increased tearing or lacrimation.
  • Temporary blurred vision.
  • Mild allergic conjunctivitis.
  • Mild corneal irritation.

Serious or Rare Side Effects

  • Corneal ulceration or erosion.
  • Severe allergic reaction including anaphylaxis.
  • Persistent corneal edema leading to visual impairment.
  • Vision loss.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Toxic keratitis.

Precautions & Warnings

When using Ophtesic, consider the following safety measures.

  • Allergy assessment: avoid if known hypersensitivity to lidocaine or amide anesthetics.
  • Corneal integrity: do not use on eyes with active corneal disease or epithelial defects.
  • Ocular infection: use with caution in the presence of bacterial or viral eye infections.
  • Pregnancy: safety not established; use only if clearly needed after risk‑benefit evaluation.
  • Systemic absorption: limit application to prevent systemic toxicity, especially in children.
  • Store at controlled room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Ophtesic may interact with other medications; awareness of potential interactions helps ensure safety.

Major Interactions (Avoid)

  • Systemic local anesthetics: concurrent use may increase risk of systemic toxicity.
  • Class I antiarrhythmics (e.g., quinidine, procainamide): additive cardiac effects.
  • Beta‑blockers: may potentiate bradycardia.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors: may affect lidocaine metabolism.
  • Alpha‑2 agonists (e.g., clonidine): may enhance hypotensive effects.
  • Other ophthalmic drugs: may alter absorption or efficacy.

Frequently Asked Questions

Ophtesic is a sterile ophthalmic solution containing lidocaine hydrochloride that provides temporary topical anesthesia of the eye. It is used during diagnostic examinations, minor ocular surgeries, and procedures such as contact lens fitting to reduce discomfort and facilitate accurate assessment.

Lidocaine blocks voltage‑gated sodium channels on nerve fibers in the ocular surface, preventing the influx of sodium ions required for depolarization. This reversible inhibition stops nerve impulse transmission, resulting in localized loss of sensation without affecting surrounding tissues.

The specific dose and frequency of Ophtesic are determined by the prescribing clinician based on the procedure, patient age, and ocular condition. Healthcare professionals select the appropriate volume and concentration to achieve adequate anesthesia while minimizing exposure.

Safety data for Ophtesic in pregnancy and lactation are limited. It should be used only if clearly needed after a careful risk‑benefit assessment by the prescriber. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks with their healthcare provider.

To request Ophtesic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Ophtesic contains lidocaine, an amide‑type anesthetic known for rapid onset and reliable depth of anesthesia. Compared with ester‑type agents such as proparacaine, lidocaine often provides a slightly longer duration of effect and a well‑established safety profile for short‑term ocular use.

Ophtesic should be stored at controlled room temperature, protected from light and moisture, and kept in its original sealed container. Avoid freezing or exposing the solution to extreme temperatures, and discard any product that appears cloudy or contaminated.

Ophtesic is applied topically to the ocular surface as a sterile drop or small volume instillation. The prescriber directs the patient or clinician on the exact number of drops, timing before the procedure, and any necessary precautions to ensure effective anesthesia.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, corneal ulceration, persistent corneal edema, and vision loss. Immediate medical attention is required if signs of a severe reaction, such as intense pain, swelling, or sudden visual changes, occur after application.

Ophtesic should not be used by individuals with known hypersensitivity to lidocaine or other amide local anesthetics, patients with active corneal disease or epithelial defects, and those with uncontrolled ocular infections. Contraindications are determined by the prescribing clinician based on the patient’s medical history.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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