Product image of Ophtesic (Anhydrous Lidocaine Hydrochloride) supplied by GNH India

Ophtesic

Active Ingredient:
Anhydrous Lidocaine Hydrochloride
Origin:
EU

Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Ophtesic, is a local anesthetic presented as a sterile ophthalmic solution for topical ocular use. It provides rapid, reversible numbing of the corneal surface and conjunctiva, facilitating procedures such as tonometry, foreign body removal, and minor eye surgeries in adult patients. It is commonly used by ophthalmologists and optometrists for patient comfort during examinations.

GNH India supplies Ophtesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established distribution networks and regulatory compliance across EU and other markets.

Manufacturer / TM Owner

Laboratoires Doliage Developpement

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Indications & Clinical Uses

Ophtesic delivers lidocaine as a topical local anesthetic for ophthalmic procedures.

  • Corneal abrasion: provides analgesia to enable comfortable healing and examination.
  • Foreign body removal: numbs the ocular surface to reduce pain during extraction.
  • Tonometry: diminishes discomfort during intra‑ocular pressure measurement.
  • Minor ocular surgery: supplies local anesthesia for procedures such as conjunctival biopsy.

How It Works

  • Lidocaine exerts its effect by reversibly blocking voltage‑gated sodium channels on neuronal membranes, inhibiting the initiation and propagation of nerve impulses. This blockade prevents depolarization of peripheral sensory fibers in the cornea and conjunctiva, resulting in a rapid, localized loss of sensation without affecting deeper ocular structures.

Side Effects

Topical ocular administration of lidocaine may be associated with a range of adverse reactions.

Common Side Effects

  • Burning or stinging sensation at the application site.
  • Transient redness of the conjunctiva.
  • Temporary blurred vision.
  • Mild allergic itching or rash.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) requiring emergency care.
  • Corneal epithelial defect or ulceration with prolonged use.
  • Persistent epithelial defect leading to delayed healing.
  • Systemic toxicity (e.g., CNS symptoms such as dizziness, seizures) if excessive absorption occurs.

Precautions & Warnings

Prior to using Ophtesic, consider the following precautions:

  • Allergy assessment: avoid in patients with known hypersensitivity to lidocaine or related amide anesthetics.
  • Pregnancy: use only if the potential benefit justifies the potential risk to the fetus.
  • Breastfeeding: caution advised due to minimal systemic absorption; evaluate risk versus benefit.
  • Contact lens wearers: remove lenses before application to prevent irritation.
  • Dosage: apply only the prescribed amount and frequency to limit systemic exposure.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Ophtesic may interact with other medicines; awareness of these interactions helps ensure safety.

Major Interactions (Avoid)

  • Concurrent use of other local anesthetics: additive risk of systemic toxicity.
  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): may potentiate lidocaine‑related cardiotoxicity.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., erythromycin, cimetidine): can increase lidocaine plasma concentrations.
  • Beta‑blockers (e.g., propranolol): may enhance central nervous system effects of lidocaine.

Frequently Asked Questions

Ophtesic is a sterile ophthalmic solution containing lidocaine that provides local anesthesia of the cornea and conjunctiva. It is used to relieve pain and discomfort during eye examinations, tonometry, removal of foreign bodies, and minor ocular surgical procedures.

Lidocaine blocks voltage‑gated sodium channels on sensory nerve fibers in the eye. By preventing sodium influx, it stops the generation and propagation of nerve impulses, producing a rapid and reversible loss of sensation in the treated ocular tissues.

The prescribed dose of Ophtesic is determined by the treating clinician based on the specific procedure and patient factors. Typically, a few drops are instilled onto the ocular surface shortly before the intended intervention, following the prescriber’s instructions.

Safety data for lidocaine ophthalmic use in pregnancy and lactation are limited. It should be used only if the potential therapeutic benefit justifies any potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To order Ophtesic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ophtesic contains lidocaine, an amide‑type anesthetic with a rapid onset and moderate duration. Compared with ester‑type agents such as proparacaine or tetracaine, lidocaine often provides a slightly longer anesthetic window and a well‑characterised safety profile, making it a common choice for many ophthalmic procedures.

Ophtesic should be stored at ambient temperature, protected from light and moisture, and kept in its original container. Do not freeze the product. Once opened, use within the period recommended by the manufacturer and discard any solution that appears cloudy or contaminated.

Ophtesic is applied topically to the eye as a sterile drop. The prescriber directs the number of drops and the timing relative to the procedure. The patient should keep the eyelids closed for a short period after instillation to allow adequate absorption.

Serious risks, although rare, include severe allergic reactions such as anaphylaxis, corneal epithelial defects or ulceration with prolonged use, and systemic toxicity (e.g., central nervous system symptoms) if excessive amounts are absorbed. Immediate medical attention is required if any of these occur.

Ophtesic should not be used in individuals with a known hypersensitivity to lidocaine or other amide‑type local anesthetics. Caution is also advised for patients with severe cardiac conduction disorders, uncontrolled epilepsy, or those taking medications that may increase lidocaine levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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