Product image of Ophtesic (Anhydrous Lidocaine Hydrochloride) supplied by GNH India

Ophtesic

Active Ingredient:
Anhydrous Lidocaine Hydrochloride
Origin:
EU

Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine hydrochloride, the active ingredient in Ophtesic, is a local anesthetic presented as a sterile ophthalmic solution for ocular use. It provides temporary surface anesthesia for eye examinations and minor procedures.
GNH India supplies Ophtesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Doliage Developpement

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Indications & Clinical Uses

  • Ophtesic, a lidocaine‑based ophthalmic anesthetic, provides temporary surface anesthesia for ocular procedures.
  • Ocular surface anesthesia: numbs the cornea and conjunctiva to facilitate painless examinations.
  • Diagnostic eye examinations: enables comfortable slit‑lamp, tonometry or fluorescein staining procedures.
  • Minor ocular surgery: provides local anesthesia for interventions such as foreign‑body removal or laser treatment.

How It Works

  • Lidocaine hydrochloride blocks voltage‑gated sodium channels in neuronal membranes of ocular surface nerves, preventing the initiation and propagation of action potentials. This inhibition stops nerve impulse transmission, resulting in localized loss of sensation without affecting deeper ocular structures.

Side Effects

Ophtesic may cause transient ocular irritation or allergic responses.

Common Side Effects

  • Burning or stinging sensation at the application site
  • Redness of the conjunctiva
  • Excessive tearing
  • Temporary blurred vision
  • Mild eyelid edema
  • Localized itching or mild rash

Serious or Rare Side Effects

  • Corneal epithelial toxicity or ulceration
  • Severe allergic reaction (anaphylaxis)
  • Persistent visual impairment
  • Secondary ocular infection
  • Significant intraocular pressure rise
  • Systemic lidocaine toxicity (rare with ocular use)

Precautions & Warnings

  • Before using Ophtesic, consider the following safety measures.
  • Allergy assessment: confirm no known hypersensitivity to lidocaine or amide anesthetics.
  • Contact lens use: remove lenses prior to administration.
  • Corneal integrity: avoid use on compromised corneal epithelium.
  • Systemic absorption: limit use in patients with severe cardiac conduction disorders.
  • Pregnancy and lactation: use only if benefit outweighs risk and after prescriber consultation.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Ophtesic can interact with other medications; monitor patients accordingly.

Major Interactions (Avoid)

  • Systemic lidocaine‑containing products: may increase total lidocaine exposure.
  • Class I antiarrhythmic drugs (e.g., quinidine, procainamide): additive cardiac effects.
  • Beta‑blockers: potential enhanced bradycardia if systemic absorption occurs.

Moderate Interactions (Monitor Closely)

  • Other ophthalmic anesthetics: cumulative local effect.
  • Topical vasoconstrictors: may alter ocular absorption.
  • Alcohol‑containing eye drops: may increase irritation.

Frequently Asked Questions

Ophtesic is an ophthalmic anesthetic used to provide temporary surface numbness of the eye. It is indicated for ocular surface anesthesia during examinations, diagnostic procedures such as slit‑lamp assessment, and minor ocular surgeries like foreign‑body removal or laser treatment.

Lidocaine hydrochloride blocks voltage‑gated sodium channels in the nerve fibers of the ocular surface. By preventing sodium influx, it stops the generation and propagation of nerve impulses, resulting in localized loss of sensation without affecting deeper ocular structures.

The specific dose and volume of Ophtesic are determined by the prescribing clinician based on the procedure, patient age, and ocular condition. Healthcare professionals should follow the product label and clinical guidelines when selecting the appropriate amount.

Safety data for Ophtesic in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and after a thorough assessment by the prescriber.

To order Ophtesic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ophtesic contains lidocaine, an amide‑type local anesthetic, offering rapid onset and reliable surface numbness. Compared with ester‑type agents such as proparacaine, lidocaine generally provides a slightly longer duration of anesthesia but shares a similar safety profile when used correctly.

Ophtesic should be stored at room temperature, below 25 °C, in its original sealed container. Protect the product from direct sunlight, moisture and extreme temperatures to maintain sterility and potency.

Ophtesic is applied topically to the ocular surface as a sterile drop. The prescriber determines the number of drops and timing based on the intended procedure. Patients should avoid touching the dropper tip to the eye or surrounding tissues to preserve sterility.

Serious risks, though rare, include corneal epithelial toxicity, severe allergic reactions such as anaphylaxis, persistent visual disturbances, and secondary ocular infection. Immediate medical attention is required if any of these events occur.

Ophtesic should not be used in individuals with a known hypersensitivity to lidocaine, other amide anesthetics, or any component of the formulation. Caution is also advised for patients with significant cardiac conduction disorders or compromised corneal epithelium.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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