Ophthajod (Povidone, Iodinated)

Ophthajod is a povidone‑iodine preparation used for ocular antisepsis and infection control.

• Pre‑operative eye preparation: reduces microbial load before intra‑ocular surgery.
• Conjunctival infection prophylaxis: helps prevent bacterial conjunctivitis after trauma.
• Minor eye injury care: limits bacterial colonisation in superficial corneal abrasions.
• Post‑operative wound care: supports healing by preventing infection after ocular procedures.

• Povidone‑iodine releases free iodine when applied to tissues. The iodine penetrates microbial cell walls, oxidises essential proteins and nucleic acids, and disrupts metabolic pathways, resulting in rapid broad‑spectrum bactericidal, virucidal, fungicidal and protozoacidal activity without relying on host immune mechanisms.

Ophthajod may cause local ocular reactions.

Common Side Effects

• Stinging or burning sensation upon instillation.
• Temporary redness of the conjunctiva.
• Mild tearing or increased lacrimation.
• Slight blurred vision that resolves quickly.
• Mild eyelid swelling.
• Discomfort that diminishes with continued use.

Serious or Rare Side Effects

• Allergic reaction presenting as severe itching, swelling, or rash.
• Corneal epithelial damage or ulceration.
• Persistent eye pain or photophobia.
• Vision loss not attributable to underlying disease.
• Anaphylaxis requiring emergency care.
• Significant intra‑ocular inflammation.

Before using Ophthajod, consider the following safety measures.

• Allergy assessment: avoid if the patient has a known iodine or povidone‑iodine hypersensitivity.
• Pregnancy and lactation: use only if clearly indicated and benefits outweigh potential risks.
• Contact lens wearers: remove lenses prior to application and wait before reinserting.
• Duration of therapy: limit use to the period prescribed by the eye care professional.
• Surgical guidance: follow specific surgeon instructions regarding timing and concentration.
• Store at room temperature: keep in the original container, protect from light and moisture.

Ophthajod can interact with other ophthalmic agents.

Major Interactions (Avoid)

• Concurrent use with other iodine‑based antiseptics: may cause excessive irritation.
• Systemic thyroid medication: high iodine exposure could affect thyroid function.

Moderate Interactions (Monitor Closely)

• Contact lens solutions: may reduce efficacy or increase toxicity.
• Topical corticosteroids: could mask signs of irritation.
• Other eye drops containing preservatives: stagger administration to minimise discomfort.
• Antifungal eye preparations: monitor for additive ocular surface effects.