Product image of Optalgin Neo (Metamizole Sodium Monohydrate) supplied by GNH India

Optalgin Neo

Active Ingredient:
Metamizole Sodium Monohydrate
Origin:
EU

Optalgin Neo (Metamizole Sodium Monohydrate)

Metamizole sodium, the active ingredient in Optalgin Neo, is a pyrazolone analgesic presented as an oral formulation for oral use. It is indicated for mild to moderate pain, fever, postoperative pain and colic or visceral pain in adult patients.
GNH India supplies Optalgin Neo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Gyógyszergyár Zrt

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Indications & Clinical Uses

Optalgin Neo, a pyrazolone analgesic, is used to manage several pain‑related conditions and fever.

  • Pain: provides relief of mild to moderate nociceptive pain.
  • Fever: reduces elevated body temperature.
  • Post‑operative pain: offers analgesia after surgical procedures.
  • Colic and visceral pain: alleviates abdominal cramping and visceral discomfort.

How It Works

  • Metamizole sodium inhibits cyclooxygenase enzymes, decreasing prostaglandin synthesis, which reduces inflammation and pain signaling. It also exerts central analgesic effects by modulating spinal pain pathways, contributing to its antipyretic activity. The combined peripheral and central actions result in effective relief of pain and fever.

Side Effects

Adverse reactions may occur with Metamizole sodium use.

Common Side Effects

  • Nausea: occasional upset stomach and vomiting.
  • Dizziness: transient light‑headedness or vertigo.
  • Rash: mild skin irritation or erythema.
  • Headache: mild to moderate head pain.

Serious or Rare Side Effects

  • Agranulocytosis: severe reduction in white blood cells, potentially life‑threatening.
  • Anaphylaxis: acute allergic reaction with respiratory distress.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic or renal impairment: abnormal liver enzymes or reduced kidney function.

Precautions & Warnings

Metamizole sodium should be used with caution and under medical supervision.

  • Medical supervision: ensure prescription and monitoring by a healthcare professional.
  • Blood count monitoring: regular hematologic tests to detect agranulocytosis.
  • Hypersensitivity: avoid in patients with known allergy to pyrazolones.
  • Renal/hepatic impairment: adjust use in patients with compromised kidney or liver function.
  • Concomitant pyrazolones: do not combine with other drugs of the same class.
  • Store at below 25°C: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Metamizole sodium can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Myelosuppressive agents: increased risk of severe blood dyscrasias.
  • Anticoagulants: heightened bleeding tendency.
  • Other NSAIDs: elevated gastrointestinal bleeding risk.
  • Drugs causing agranulocytosis: additive risk of white‑blood‑cell suppression.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible alteration of renal electrolyte balance.
  • Antihypertensives: may enhance potassium loss and affect blood pressure control.
  • Alcohol: can increase gastrointestinal irritation and central nervous system effects.

Frequently Asked Questions

Optalgin Neo contains Metamizole sodium, a prescription analgesic used to treat mild to moderate pain, reduce fever, manage postoperative discomfort, and relieve colic or visceral abdominal pain in adult patients.

Metamizole sodium works by inhibiting cyclooxygenase enzymes, which lowers prostaglandin production, reducing inflammation and pain signals. It also has central nervous system effects that contribute to its analgesic and antipyretic actions.

The appropriate dose of Optalgin Neo is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, and individual health factors. Patients should follow the prescriber’s instructions and not self‑adjust the dosage.

Safety of Metamizole sodium in pregnancy or while breastfeeding has not been definitively established. Healthcare providers should evaluate the risk‑benefit profile before prescribing to pregnant or lactating women, and alternative treatments may be considered.

To order Optalgin Neo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Optalgin Neo (Metamizole sodium) belongs to the pyrazolone class, offering analgesic and antipyretic effects similar to NSAIDs but with a distinct mechanism. Compared with traditional NSAIDs, it may have a lower incidence of gastrointestinal irritation but carries a risk of rare blood disorders, requiring careful monitoring.

Optalgin Neo should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Maintaining these conditions helps preserve the tablet’s stability and potency throughout its shelf life.

Optalgin Neo is taken orally as directed by a healthcare professional. The tablets are swallowed whole with water, and the dosing schedule is determined by the prescriber according to the patient’s therapeutic needs.

The most serious risks include agranulocytosis, a potentially life‑threatening drop in white blood cells, severe allergic reactions such as anaphylaxis, and rare skin conditions like Stevens‑Johnson syndrome. Prompt medical attention is required if any of these symptoms appear.

Optalgin Neo should not be used by individuals with known hypersensitivity to Metamizole or other pyrazolones, patients with existing severe blood disorders, or those taking other myelosuppressive agents without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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