Product image of Optax (Oxybuprocaine Hydrochloride, Fluorescein Sodium) supplied by GNH India

Optax

Active Ingredient:
Oxybuprocaine Hydrochloride, Fluorescein Sodium
Origin:
EU

Optax (Oxybuprocaine Hydrochloride, Fluorescein Sodium)

Oxybuprocaine Hydrochloride, the active ingredient in Optax, is an ophthalmic local anesthetic presented as an ophthalmic solution for topical ocular use. It provides rapid, reversible anesthesia of the corneal surface for eye examinations and minor procedures, and when combined with Fluorescein Sodium it enables corneal and conjunctival staining for diagnostic evaluation.

GNH India supplies Optax as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures quality compliance with EU standards and provides reliable global distribution.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

Optax, containing an ophthalmic local anesthetic and diagnostic dye, is employed in ocular surface procedures and diagnostic assessments.

  • Diagnostic eye examinations: provides corneal and conjunctival staining for enhanced visualization.
  • Minor ocular procedures (e.g., foreign body removal): delivers topical anesthesia to reduce patient discomfort.
  • Contact lens fitting and tear film evaluation: enables assessment of ocular surface integrity and tear distribution.

How It Works

  • Oxybuprocaine Hydrochloride blocks voltage‑gated sodium channels in corneal nerve fibers, producing reversible local anesthesia of the ocular surface. Fluorescein Sodium binds to plasma proteins and adheres to damaged epithelial cells, imparting a bright yellow fluorescence under cobalt‑blue light that highlights corneal and conjunctival defects for diagnostic evaluation.

Side Effects

Adverse reactions to Optax may range from mild irritation to rare serious events.

Common Side Effects

  • Stinging or burning sensation upon instillation.
  • Transient blurred vision.
  • Conjunctival hyperemia.
  • Mild allergic conjunctivitis.
  • Temporary eyelid edema.

Serious or Rare Side Effects

  • Corneal epithelial toxicity.
  • Severe allergic reaction (anaphylaxis).
  • Persistent corneal ulceration.
  • Intraocular pressure elevation.

Precautions & Warnings

When using Optax, consider the following precautions to ensure safety and efficacy.

  • Allergy assessment: avoid use in patients with known hypersensitivity to oxybuprocaine, fluorescein or related compounds.
  • Contact lens wear: remove contact lenses before administration and wait before reinserting.
  • Active eye infection: do not apply unless directed by a clinician.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation.
  • Concomitant ocular medications: assess potential interactions before co‑administration.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Optax may interact with other ophthalmic agents; consider the following.

Major Interactions (Avoid)

  • Systemic sulfonamides: may increase risk of severe allergic reactions to fluorescein.
  • Topical anesthetic agents: combined use can lead to additive corneal toxicity.
  • Preservative‑containing contact lens solutions: may cause heightened ocular irritation.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: may increase ocular surface irritation.
  • Anticholinergic ophthalmic drops: may affect pupil response during diagnostic staining.
  • Topical beta‑blockers: monitor intraocular pressure if used concurrently.

Frequently Asked Questions

Optax is an ophthalmic solution that combines a local anesthetic with a diagnostic dye. It is used to provide temporary numbness of the cornea for eye examinations and minor procedures, and to stain the ocular surface with fluorescein for enhanced visualization of corneal abrasions, ulcers, and tear film patterns.

Oxybuprocaine blocks voltage‑gated sodium channels on corneal nerve endings, preventing the initiation and propagation of nerve impulses. This reversible blockade results in rapid loss of sensation on the ocular surface, allowing clinicians to perform examinations or minor interventions without causing pain to the patient.

The dose of Optax is determined by the prescribing clinician. Typically, one to two drops are instilled into the conjunctival sac of the affected eye shortly before the procedure or diagnostic staining, but the exact volume and frequency depend on the specific clinical situation.

Safety data for Optax in pregnancy and lactation are limited. It should only be used when clearly needed, after a careful risk‑benefit assessment by the treating physician. Women who are pregnant or breastfeeding should discuss potential risks with their healthcare provider before use.

To order Optax, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The team then replies with pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Optax combines oxybuprocaine, a fast‑acting anesthetic, with fluorescein for diagnostic staining. Compared with agents such as proparacaine or tetracaine, oxybuprocaine provides a similarly rapid onset but may have a slightly shorter duration. The added fluorescein component gives Optax a dual function that single‑agent anesthetics lack, making it useful when both anesthesia and surface visualization are required.

Optax should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed in its original packaging. Do not freeze the solution, and discard any product that appears discolored or contains particles.

Optax is applied topically to the eye. The patient should tilt the head back slightly, pull down the lower eyelid to create a small pocket, and instill the prescribed number of drops into the conjunctival sac. After administration, the patient should keep the eye closed for a few seconds to allow even distribution.

Serious risks, although rare, include corneal epithelial toxicity, severe allergic reactions such as anaphylaxis, persistent corneal ulceration, and a possible rise in intraocular pressure. Any signs of intense pain, vision loss, swelling, or allergic symptoms should prompt immediate medical evaluation.

Optax should not be used in individuals with known hypersensitivity to oxybuprocaine, fluorescein, or any excipients in the formulation. It is also contraindicated in eyes with active severe infection unless directed by a specialist, and in patients where the risk of corneal toxicity outweighs the clinical benefit.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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